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-  2019 

Loss of Hepatic Oscillatory Fed microRNAs Abrogates Refed Transition and Causes Liver Dysfunctions

DOI: https://doi.org/10.1016/j.celrep.2019.01.087

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Abstract:

? Anticipatory hepatic fed miRNAs are essential to attenuating fasting response ? RISC association of miRNA-mRNA pairs oscillates during fed-fast cycles in the liver ? Convergent additive action of miRNAs governs metabolic and mitochondrial homeostasis ? Scavenging fed miRNAs impairs refed transition and affects whole-body energetic

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