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- 2019
Evolution of Relapse-Proficient Subclones Constrained by Collateral Sensitivity to Oncogene Overdose in Wnt-Driven Mammary CancerDOI: https://doi.org/10.1016/j.celrep.2018.12.096 Abstract: ？ Wnt-driven mammary cancers maintain dependence on sub-maximal Wnt signaling ？ Rescue mutations destined to subvert targeted therapy carry a fitness cost ？ Oncogene overdose imposes negative selection, leading to turnover of rescue subclone
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