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-  2019 

Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease

DOI: https://doi.org/10.1016/j.celrep.2018.12.094

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Abstract:

? LXRαS196A induces liver steatosis and prevents cholesterol accumulation ? LXRαS196A reduces progression to hepatic inflammation and fibrosis ? LXRαS196A modulates hepatic chromatin acetylation ? LXRαS196A reveals unique dual LXRα phosphorylation and diet-responsive gene

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