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OALib Journal期刊
ISSN: 2333-9721
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-  2019 

Axonogenesis Is Coordinated by Neuron-Specific Alternative Splicing Programming and Splicing Regulator PTBP2

DOI: https://doi.org/10.1016/j.neuron.2019.01.022

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Abstract:

? Axon formation is orchestrated by neural-specific alternative splicing programming ? Early axonogenesis-associated splicing changes are governed by PTBP2 ? Splicing-dependent functional changes of SHTN1 in actin binding and polymerization ? PTBP2 depletion impedes axon growth while stimulating axon specificatio

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