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-  2019 

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

DOI: https://doi.org/10.1016/j.cell.2018.11.030

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Abstract:

? Ribonucleoprotein particles are associated with endosomes in axons ? Rab7a endosomes provide sites for axonal local translation ? Rab7a endosomes support axonal synthesis of survival factors ? CMT2B-Rab7a mutations affect axonal translation and mitochondrial integrit

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