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- 2019
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric ComplexDOI: https://doi.org/10.1016/j.celrep.2019.03.061 Abstract: ？ LSD2 demethylase binds nucleosomes by discrete promiscuity at multiple sites ？ Nucleosomal DNA represents an intrinsic barrier to histone demethylation ？ NPAC has a rigid and catalytically inert oligomerization core and flexible arms ？ The NPAC/LSD2 multifunctional enzyme complex modifies transcribed chromati
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