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OALib Journal期刊
ISSN: 2333-9721
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-  2019 

Structure of Human Mitochondrial Translation Initiation Factor 3 Bound to the Small Ribosomal Subunit

DOI: https://doi.org/10.1016/j.isci.2018.12.030

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Abstract:

? High-resolution cryo-EM study of the mammalian 28S mitoribosome-IF3mt complex ? Interaction between the 28S and IF3mt's NTD explains NTD's unusual high affinity ? Provides insights into role of IF3mt's N-terminal extension in initiator tRNA binding ? Provides insights into roles of IF3mt's CTD and C-terminal extension in mRNA sensin

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