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- 2019
Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T CellsDOI: https://doi.org/10.1016/j.ccell.2019.01.002 Abstract: ？ B7-H3 is overexpressed in solid tumors but rarely in normal tissues ？ B7-H3.CAR T cells show potent antitumor activity against solid tumor cells ？ 4-1BB co-stimulation in B7-H3.CAR T cells promotes resistance to PD-L1 ？ B7-H3.CAR T cells are effective in a syngeneic tumor model without causing toxicit
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