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- 2019
Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCsDOI: https://doi.org/10.1016/j.stem.2019.03.012 Abstract: ？ KLFs foster EGA by activating enhancers embedded in young TEs (TEENhancers) ？ TEENhancers confer a degree of species specificity to early genome activation ？ TEENhancers stimulate the expression of KZFPs responsible for their repression ？ These KZFPs in turn facilitate TEENhancers’ exaptation as tissue-specific regulator
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