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-  2019 

Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes

DOI: https://doi.org/10.1016/j.celrep.2018.12.098

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Abstract:

? Systematic exploration of the chromatin landscape and regulatory basis of AMLs ? Identification of 2 main AML subtypes based on chromatin states ? Distinct genetic mutations converge at the chromatin level ? Chromatin signatures reveal diverse stemness phenotypes and cellular consequence

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