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- 2019
Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate DependenciesDOI: https://doi.org/10.1016/j.celrep.2019.02.041 Abstract: ？ A robust and flexible platform for genetic screens in hPSCs ？ Essential gene profiles for hPSCs on two substrates and core hPSC fitness gene sets ？ Previously unidentified regulators of hPSC fitness (DRICH1 and others) ？ Confirmation of the TP53 pathway, PAWR, PMAIP1 as negative proliferation regulator
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