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-  2019 

Viral Infection or IFN-α Alters Mitotic Spindle Orientation by Modulating Pericentrin Levels

DOI: https://doi.org/10.1016/j.isci.2019.01.025

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Abstract:

? ZIKV infection resembles MOPDII depletion of the centrosomal protein PCNT ? Viral infection of mitotic cells results in loss of PCNT and spindle misorientation ? IFN-α exposure to mitotic cells causes spindle misorientation ? Loss of IFNAR abrogates both viral and IFN-α-induced spindle misorientatio

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