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-  2019 

Prostate Stroma Increases the Viability and Maintains the Branching Phenotype of Human Prostate Organoids

DOI: https://doi.org/10.1016/j.isci.2019.01.028

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Abstract:

? Co-culture with human primary prostate stroma improves epithelial organoid viability ? Stromal cell contact in co-culture directs epithelial organoid branching ? Prostate stromal cells express morphogenic factors unique from non-prostate fibroblasts ? Co-culture with stroma maintains AMACR and increases survival of cancer derived-organoid

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