Higher-Order Thalamocortical Inputs Gate Synaptic Long-Term Potentiation via Disinhibition

？ Activation of higher-order (HO) thalamic inputs facilitates intracortical LTP ？ HO inputs increase VIP and PV interneuron (IN) activity and decrease SST IN activity ？ The activation of VIP INs disinhibits L2/3 pyramidal neurons (PNs) ？ The HO-to-VIP circuit gates the intracortically driven LTP on PN