ACOT12-Dependent Alteration of Acetyl-CoA Drives Hepatocellular Carcinoma Metastasis by Epigenetic Induction of Epithelial-Mesenchymal Transition

？ Down-regulation of ACOT12 is correlated with metastasis and poor prognosis of HCC ？ ACOT12 functionally suppresses HCC metastasis ？ ACOT12 regulates acetyl-coA metabolism and histone acetylation ？ Down-regulation of ACOT12 promotes HCC metastasis by epigenetic induction of TWIST