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-  2019 

CaV2.1 α1 Subunit Expression Regulates Presynaptic CaV2.1 Abundance and Synaptic Strength at a Central Synapse

DOI: https://doi.org/10.1016/j.neuron.2018.11.028

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Abstract:

? Ca V2.1 dominate presynaptic active zones are not fully occupied by Ca V2.1 channels ? Presynaptic Ca V2.1 channel numbers can increase regardless of developmental state ? Higher synaptic vesicle release probability with increased Ca V2.1 channel numbers ? Ca V2.1 completely competes away Ca V2.2 channels, but not vice vers

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