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OALib Journal期刊
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-  2019 

The Circadian Clock Protein CRY1 Is a Negative Regulator of HIF-1α

DOI: https://doi.org/10.1016/j.isci.2019.02.027

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Abstract:

? Hypoxia and HIFs affect the circadian rhythm ? CRY1 directly interacts with both HIF-1α and HIF-2α ? CRY1 inhibits binding of HIFs to its target gene promoters ? The CRY1-HIFα interaction has opposite roles on cellular growth and migratio

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