Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids

？ In vivo isotope tracing provides a quantitative framework of tissue BCAA oxidation ？ Genetic and pharmacological perturbations alter the distribution of BCAA oxidation ？ Insulin acutely increases BCAA oxidation selectively in striated muscle ？ Insulin-resistant mice shunt BCAA oxidation from liver and fat towards muscl