|
|
- 2019
Hitting Undruggable Targets: Viewing Stabilized Peptide Development through the Lens of Quantitative Systems PharmacologyDOI: https://doi.org/10.1016/j.tibs.2018.11.008 Abstract: Stabilized peptides have the potential to hit currently ‘undruggable’ intracellular targets. However, reaching the cytosol remains one of the most challenging steps in delivery, and current knowledge of how physicochemical properties impact on membrane permeability is incomplete
|
