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- 2019
Mechanism of Bidirectional Leading-Strand Synthesis Establishment at Eukaryotic DNA Replication OriginsDOI: https://doi.org/10.1016/j.molcel.2018.10.019 Abstract: ? Mapping of leading-strand start sites at two S. cerevisiae DNA replication origins ? Leading-strand synthesis is established from “lagging-strand” primers ? Pol δ likely plays a key role in establishing all nascent leading strands ? Replisomes remain interdependent until new leading strands are establishe
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