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OALib Journal期刊
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-  2019 

Mechanism of Bidirectional Leading-Strand Synthesis Establishment at Eukaryotic DNA Replication Origins

DOI: https://doi.org/10.1016/j.molcel.2018.10.019

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? Mapping of leading-strand start sites at two S. cerevisiae DNA replication origins ? Leading-strand synthesis is established from “lagging-strand” primers ? Pol δ likely plays a key role in establishing all nascent leading strands ? Replisomes remain interdependent until new leading strands are establishe

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