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-  2019 

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance

DOI: https://doi.org/10.1016/j.stem.2019.02.012

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Abstract:

? Vitamin B3 analogs improve hematopoietic stem cell (HSC) and progenitor function ? Nicotinamide riboside (NR) increases mitochondrial recycling in HSCs ? In vitro NR exposure induces asymmetric mitochondrial distribution in dividing HSCs ? NR dietary supplementation improves survival after HSC transplantation in mic

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