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-  2019 

Regulation of NGF Signaling by an Axonal Untranslated mRNA

DOI: https://doi.org/10.1016/j.neuron.2019.02.011

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Abstract:

? Tp53inp2 is the most abundant mRNA in SN axons but is not translated ? Tp53inp2 transcript interacts with the TrkA receptor to regulate NGF signaling ? In SNs, Tp53inp2 functions independently of its protein-coding capacity ? Tp53inp2 transcript is essential for axon growth and target innervation in viv

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