|
|
- 2019
Retinoic Acid Induces Hyperactivity, and Blocking Its Receptor Unmasks Light Responses and Augments Vision in Retinal DegenerationDOI: https://doi.org/10.1016/j.neuron.2019.02.015 Abstract: ？ Photoreceptor degeneration leads to retinal ganglion cell hyperactivity ？ Hyperactivity is triggered by overproduction of retinoic acid (RA) ？ Blocking the RA receptor with drug or gene therapy reduces hyperactivity ？ RA receptor blockade augments light-evoked behaviors in vision-impaired mic
|
