More Than Just Acetates: PhI(OAc)2 Enables C–H Halogenation of Arenes

In this issue of Chem, Nagib and co-workers report an operationally simple approach for direct C–H halogenation of arenes and (hetero)arenes through in situ activation of commercially available PhI(OAc) 2. The resulting non-symmetrical iodanes offer chemists new tools for the mild halogenation of arene scaffolds with exquisite selectivity and tunability