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-  2019 

A Gradient in Metaphase Tension Leads to a Scaled Cellular Response in Mitosis

DOI: https://doi.org/10.1016/j.devcel.2019.01.018

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Abstract:

? The magnitude of centromere tension is sensed by the cell during mitosis ? The cellular response to low metaphase tension is dose dependent in nature ? The primary cellular response to low metaphase tension is detachment of kinetochores ? Tension-dependent phosphorylation of the kinetochore underlies the tension respons

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