Still Searching for Specialized Ribosomes

Reporting in Developmental Cell, Cenik et al. (2019) Cenik E.S. Meng X. Tang N.H. Hall R.N. Arribere J.A. Cenik C. Jin Y. Fire A. Maternal ribosomes are sufficient for tissue diversification during embryonic development in C. elegans. Dev. Cell. 2019; 48 ( this issue) : 811-826 Google Scholar show that the maternal ribosome supply is sufficient for C. elegans embryonic development, arguing against tissue-specific specialized ribosomes in this context. Examination of ribosomal requirement with the genetic tool kit presented in Artiles et al. (2019) Artiles K.L. Fire A.Z. Fr？kj？r-Jensen C. Assessment and maintenance of unigametic germline inheritance for C. elegans. Dev. Cell. 2019; 48 ( this issue) : 827-839 Google Scholar suggests a checkpoint that prevents uncoordinated growth