Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity

？ scRNA-seq of pathogen-challenged lymph node identifies key cell types and pathways ？ Antigen-specific immunity is driven by antigen-carrying dendritic cells and monocytes ？ Antigen-specific cytokines drive population heterogeneity at the cellular level ？ Crosstalk between monocytes and NK cells promotes the induction of Th1 respons