Temporal Control of Appetite by AgRP Clocks

Neuronal control of diurnal appetitive drive is not well understood. In this issue, a study by Cedernaes et al. (2019) Cedernaes J. Huang W. Ramsey K.M. Waldeck N. Cheng L. Marcheva B. Omura C. Kobayashi Y. Peek C.B. Levine D.C. et al. Transcriptional basis for rhythmic control of hunger and metabolism within the AgRP neuron. Cell Metab. 2019; 29 ( this issue) : 1078-1091 Google Scholar elucidates a key role of AgRP neuronal clocks and delineates the cell-type-specific transcriptional landscape in the temporal regulation of hunger