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- 2019
Muscle-Specific FXR1 Isoforms in Squamous Cell CancerDOI: https://doi.org/10.1016/j.trecan.2018.12.001 Abstract: The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) is upregulated in head and neck squamous cell carcinomas (HNSCCs) and expressed as at least seven isoforms in humans. Only two of these isoforms are capable of binding to RNA containing G-quadruplex structures. We suggest that these unique isoforms play a role in the pathogenesis of HNSCC
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