C3 glomerulopathy disease

C3 glomerulopathy is a recently defined disease that encompasses a group of kidney diseases caused by abnormal control of complement activation. C3G is characterized bydeposition of dominant complement C3 with absence/traces of immunoglobulins in the glomeruli. C3G may be classified into dense deposit disease (DDD) and C3 glomerulonephritis (C3GN). DDD and C3GN are rare forms of glomerulonephritis that affect both children and adults. In treatment C3G include on specific treatment, plasma therapy, immunsupressive and complement inhibition