DOES INSULIN RESISTANCE AND IMPAIRED GLUCOSE TOLERANCE AFFECT SERUM ANDROGEN LEVELS IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME?

Objective: In this study, we investigated the effect of insulin resistance on the waist circumference - BMI - Androjeblerin (Total Testosterone, DHEAS04) in 209 cases with Policystic Over Syndrome. Materials and Methods:. The study was performed with 18 and 40 years of age and policystic ovary syndrome 209 cases. Basal hormone levels of patients, serum androgens; (DHEASO4), total testosterone (TT) and free testosterone (ST) levels were measured. Insulin resistance was assessed by Homeostatic Model Assessment (HOMA-IR) method. In addition, Body Mass Index (BMI), waist circumference, menstrual alignment, fertility status were assessed. A modified Ferriman-Galway scoring photo was used in hirsutism evaluation. The results were evaluated using the Oneway ANOVA test and Chi-Square test, Fisher test. Results: There was a statistically significant relationship between insulin resistance and BMI and waist circumference. No statistically significant relationship was found between hirsutism, DHEAS, total testosterone and free testosterone. There was no statistically significant relationship between impaired glucose tolerance and BMI levels, waist circumference, hirsutism, DHEAS, total testosterone and free testosterone. Keywords: Polycystic Ovary Syndrome, Insulin Resistance, Impaired Glucose Tolerance, Serum Androgen Leve