Adult Onset Langerhans Cell Histiocytosis

Langerhans cell histiocytosis (LCH) is a rare disease characterized by clonal and neoplastic proliferation of Langerhans cells. It is most commonly seen in children but can be seen at any age. Clinical findings depend on the organ system involved. The diagnosis of LCH is made histopathologically. The treatment is planned according to the organ system of the disease, the prevalence of the lesions and the presence of specific organ dysfunction. We aimed to discuss the clinical, radiological and histapatological findings of a 33-year-old man with femoral involvement at adulthood and discuss the current literature