The relationship between monocyte to HDL cholesterol ratio, carotid intima-media thickness and type 2 diabetes mellitus

Aim: Diyabetes mellitus (DM) is a maj？r risk factor for atheroscleros. Circulating monocyte count plays an important role for new atherosclerotic plaque development. Also, there is a strong inverse relationship between high density lipoprotein cholesterol (HDL) and atherosclerosis. monocyte count/HDL ratio (MHR) is a novel inflammatory marker for atheroscleros. Carotid intima-media thickness (CIMT) can predict the presence or absence of coronary artery disease (CAD). I aimed to investigate relationship between CIMT, MHR and type 2 DM Methods: A total of 120 patients were divided into two groups (with type2 DM group = 60, control group: 60). Baseline characteristics, laboratory parameters, MHR and CIMT were recorded and compared between groups. Results: The Diabetes group had considerable higher CIMT, MHR levels compared to the control (p<0.001,p<0,001 respectively ). Also, CIMT levels showed significant correlation with blood glucose level (r=0.474, p<0.001). On the contrary, HDL levels were higher in the control group (p=0.010). Conclusion: In conclusion, I found significantly higher MHR and CIMT in the diabetic group and thus I think MHR, which is an easily calculated index, can be used in the daily clinical practice as an indicator of atherosclerosis in Type 2 DM patients