Do Complete Blood Count Parameters Show the Functional Level in Stroke Patients?

Objective: Inflammation has a crucial role in the pathogenesis of stroke, and in recent years, complete blood parameters and their derivatives have led to poor prognosis in the course of various diseases. We aimed to elucidate the relation of various whole blood parameters and derivatives with the functional levels of stroke patients. Matherial and Methods: Patients diagnosed with stroke in our clinic between 2016 and 2017 years were retrospectively analyzed. All patients were recorded for age, gender, etiology, involved side, spasticity, functional ambulatory scale (FAS), upper and lower extremity Brunnstrom grades. Acute phase reactants, erythrocyte sedimentation rate (ESR), C-reactive protein (RBC), and complete blood count and sub-parameters of all patients at the time of admission, white blood cell (WBC), erythrocyte distribution width (RDW), platelet distribution width (PDW), mean platelet volume reactive protein (CRP) were recorded. Results: Fifty-five (55) male (63.2%) and 30 female (34.5%) were included in the study at the age range of 32-85 years. Sixty-four percent (64%) of the patients were diagnosed with stroke for less than 1 year, 86.2% was ischemic, and 50.6% was right-sided. There was no spasticity in 25.3% of the patients. Ashworth grade 1 spasticity was the most frequently observed in 23% of the cases with spasticity. Functional levels were most frequently with a ratio of 20.7% FAS 3, upper extremity with a ratio of 32.2% was Brunnstrom grade 3, at lower extremity was Brunstrom grade 5 with a ratio of 28.7%. Conclusion: Inflammatory parameters provide information about the functional level in stroke patients. Systemic inflammation that triggers an inflammatory reaction or inhibition of neuronal pathways is a potential future therapeutic target in stroke patients.therapeutic target in stroke patients