Pregnancy in a sickle cell patient is a source of maternal and perinatal morbidities. Thromboembolic diseases of which Deep Vein Thrombosis (DVT) is one of the complications. The frequency of the latter is poorly assessed. Very few studies have been done on this topic. We report a case of DVT in a 35-year-old patient with sickle cell SS pregnant with 27SA diagnosed and cared for at the Maternity Issaka Gazobi (MIG) in Niamey. The management was based on low molecular weight heparin combined with preventive measures against sickle cell anemia and a planned cesarean section which led to a favorable maternal and perinatal prognosis.
References
[1]
Baurain, J.F. (2013) Prévention et traitement des thromboembolies veineuses. Réunion de consensus INAMI 21 novembre 2013.
[2]
Magali, S. (2007) Suivi des grossesses et des accouchements des patientes sous traitement anticoagulant à la maternité régionale A. Pinard de Nancy. Sciences du Vivant [q-bio]. hal-01732600
[3]
Noubouossie, D. and Key, N.S. (2015) Sickle Cell Disease and Venous Thromboembolism in Pregnancy and the Puerperium. Thrombosis Research, 135, S46-S48. https://doi.org/10.1016/S0049-3848(15)50442-8
[4]
Villers, M.S., Jamison, M.G., Castro, L.M.D. and James, A.H. (2008) Morbidity Associated with Sickle Cell Disease in Pregnancy. American Journal of Obstetrics & Gynecology, 199, 125E1-125.E5. https://doi.org/10.1016/j.ajog.2008.04.016
[5]
Seaman, C.D., Yabes, J., Li, J., Moore, C.G. and Ragni, M.V. (2014) Venous Thromboembolism in Pregnant Women with Sickle Cell Disease: A Retrospective Database Analysis. Thrombosis Research, 134, 1249-1252. https://doi.org/10.1016/j.thromres.2014.09.037
[6]
Shet, A.S. and Wun, T. (2018) How I Diagnose and Treat Venous Thromboembolism in Sickle Cell Disease. Blood, 132, Article No. 1761. https://doi.org/10.1182/blood-2018-03-822593
[7]
Coumba, S. (2004) Enquête sur les connaissances et attitudes des mères face à la prise en charge des enfants drépanocytaires dans les ménages à Bamako [Thèse de doctorat en médecine]. Université de Bamako, Bamako.
[8]
Lecouffe-Desprets, M., Graveleau, J., Artifoni, M., et al. (2019) Maladies hémolytiques et thrombose veineuse: Mise au point. La Revue de Médecine Interne, 40, 232-237. https://doi.org/10.1016/j.revmed.2018.10.387
[9]
Sahabi, A. (2017) Drépanocytose et grossesse à la maternité Issaka Gazobi [Mémoire en Médecine, Gynécologie obstétrique]. Université Abdou Moumouni de Niamey, Niamey.
[10]
Porter, B., Key, N.S., Jauk, V.C., Adam, S., Biggio, J. and Tita, A. (2014) Impact of Sickle Hemoglobinopathies on Pregnancy-Related Venous Thromboembolism. American Journal of Perinatology, 31, 805-810. https://doi.org/10.1055/s-0033-1361931
[11]
Delluc, A. (2016) Prise en charge de la maladie thromboembolique au cours de la grossesse. Vocation de Sage-Femme, 15, 15-18. https://doi.org/10.1016/j.vsf.2016.01.004
[12]
Barfield, W.D., Barradas, D.T., Manning, S.E., Kotelchuck, M. and Shapiro-Mendoza, C.K. (2010) Sickle Cell Disease and Pregnancy Outcomes. American Journal of Preventive Medicine, 38, S542-S549. https://doi.org/10.1016/j.amepre.2009.12.020
[13]
Torkzad, M.R., Bremme, K., Hellgren, M., Eriksson, M.J., Hagman, A., Jörgensen, T., et al. (2010) Magnetic Resonance Imaging and Ultrasonography in Diagnosis of Pelvic Vein Thrombosis Durind Pregnancy. Thrombosis Research, 126, 107-112. https://doi.org/10.1016/j.thromres.2010.05.011
[14]
Horellou, M.H., Plu-Bureau, G. and Lepercq, J. (2014) Maladie Thromboembolique veineuse et grossesse. La Revue De Medecine Interne, 10, 356
[15]
Habibi, A., Arlet, J.B., Stankovic, K., Gellen-Dautremer, J., Ribeil, J.-A., Bartolucci, P., et al. (2015) Recommandations françaises de prise en charge de la drépanocytose de l’adulte: Actualisation 2015. La Revue de Médecine Interne, 36, S83-S84. https://doi.org/10.1016/S0248-8663(15)60002-9
[16]
Société Française d'Anesthésie et de Réanimation (2005) RPC Prévention de la maladie thromboembolique veineuse périopératoire et obstétricale. http://www.sfar.org
[17]
Camous, J., N’da, A., Etienne-Julan, M. and Stéphan, F. (2008) Anesthetic Management of Pregnant Women with Sickle Cell Disease: Effect on Postnatal Sickling Complications. Canadian Journal of Anesthesia, 55, 276-283. https://doi.org/10.1007/BF03017204
