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Application of Statistical Process Control for Setting Action Thresholds as Quality Assurance of Dose Verifications in External Beam Radiotherapy

DOI: 10.4236/ijmpcero.2022.111003, PP. 22-35

Keywords: Quality Assurance, Statistical Process Control, Action Thresholds, Dose Verification, External Beam Radiation Therapy

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Abstract:

Purpose: To test the concept of Statistical Process Control (SPC) as a Quality Assurance (QA) procedure for dose verifications in external beam radiation therapy in conventional and 3D Conformal Radiotherapy (3D-CRT) treatment of cervical cancer. Materials and Methods: A study of QA verification of target doses of 198 cervical cancer patients undergoing External Beam Radiotherapy (EBRT) treatments at two different cancer treatment centers in Kenya was conducted. The target doses were determined from measured entrance doses by the diode in vivo dosimetry. Process Behavior Charts (PBC) developed by SPC were applied for setting Action Thresholds (AT) on the target doses. The AT set was then proposed as QA limits for acceptance or rejection of verified target doses overtime of the EBRT process. Result and Discussion: Target doses for the 198 patients were calculated and SPC applied to test whether the action limits set by the Process Behavior Charts could be applied as QA for verified doses in EBRT. Results for the two sub-groups of n = 3 and n = 4 that were tested produced action thresholds which are within clinical dose specifications for both conventional AP/PA and 3D-CRT EBRT treatment techniques for cervical cancer. Conclusion: Action thresholds set by SPC were within the clinical dose specification of ±5% uncertainty for both conventional AP/PA and 3D-CRT EBRT treatment techniques for cervical cancer. So the concept of SPC could be applied in setting QA

References

[1]  Gadhi, M.A., Fatmi, S., Chughtai, G.M., et al. (2016) Verification of Absorbed Dose Using Diodes in Co-60 Radiation Therapy. Australasian Physical & Engineering Sciences in Medicine, 39, 211-219.
[2]  Janaki, M.G., Kadam, A.R., Mukesh, S., et al. (2010) Magnitude of Fatique in Cancer Patients Receiving Radiotherapy and Its Short Term Effect on Quality of Life. Journal of Cancer Research and Therapeutics, 6, 22-26.
[3]  Ndonye, P.K. (2018) Advances in Treatment of Cancer by Brachytherapy in Kenya, in Particular, Prostate Cancer. Journal of Medical Physics and Applied Sciences, 3, 1-8.
[4]  Followill, D., Van Dyk, J. and Palta, J.R. (2007) Quality Assurance: ANL Talk, Quality Assurance Principles. Argonne National Laboratories, Chicago.
[5]  Essers, M. and Mijneer, B.J. (1999) In Vivo Dosimetry during External Beam Radiotherapy. International Journal of Radiation Oncology, Biology, Physics, 43, 245-259.
https://doi.org/10.1016/S0360-3016(98)00341-1
[6]  Florino, C., Corletto, D., Mangili, P., et al. (2000) Quality Assurance by Systematic In Vivo Dosimetry; Results on a Large Cohort of Patients. Radiotherapy & Oncology, 56, 85-95.
https://doi.org/10.1016/S0167-8140(00)00195-X
[7]  AAPM (2005) Diode In Vivo Dosimetry for Patients Receiving External Beam Radiation Therapy. American Association of Physicists in Medicine.
[8]  ESTRO (2001) Practical Guidelines for the Implementation of in Vivo Dosimetry with Diodes in External Beam Radiotherapy with Photon Beams (Entrance Dose). Physics for Clinical Radiotherapy. 1st Edition, European Society for Therapeutic Radiology and Oncology, Brussels.
[9]  Podgorsak, E.B. (2005) Radiation Oncology Physics: A Handbook for Teachers and Students. International Atomic Energy Agency, Vienna, 72-74.
[10]  IAEA (2013) Development of Procedures for in Vivo Dosimetry in Radiotherapy. IAEA Human Health Report No. 8. International Atomic Energy Agency, Vienna.
[11]  Boyer, A.L. and Schultheiss, T. (1988) Effects of Dosimetry and Clinical Uncertainty on Complication-Free Local Tumor Control. Radiotherapy & Oncology, 11, 65-71.
https://doi.org/10.1016/0167-8140(88)90046-1
[12]  Brahme, A. (1984) Dosimetric Precision Requirements in Radiation Therapy. Acta Radiologica: Oncology, 23, 379-391.
https://doi.org/10.3109/02841868409136037
[13]  Pawlicki, T., Whitaker, M. and Boyer, A.L. (2005) Statistical Process Control for Radiotherapy Quality Assurance. Medical Physics, 32, 2777-2786.
https://doi.org/10.1118/1.2001209
[14]  Cozzi, L. and Fogliata-Cozzi, A. (1998) Quality Assurance in Radiation Oncology. A Study of Feasibility and Impact on Action Levels of an in Vivo Dosimetry Program during Breast Cancer Irradiation. Radiotherapy & Oncology, 47, 29-36.
https://doi.org/10.1016/S0167-8140(97)00202-8
[15]  Van Esch, A., Bogaerts, R., Kutcher, G.J. and Huyskens, D. (2000) Quality Assurance by Identifying Standards and Monitoring Treatment Preparation. Radiotherapy & Oncology, 56, 109-115.
https://doi.org/10.1016/S0167-8140(00)00190-0
[16]  Shewhart, W.A. (1931) Economic Control of Quality of Manufactured Product. D. Van Nostrand Company, Inc., New York.
[17]  British Institute of Radiology (1996) Central Axis Depth Dose Data for Use in Radiotherapy. The British Journal of Radiology, 25.

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