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Preservation of the Intercostobrachial Nerve during Axillary Dissection for Breast Cancer at the Surgical Oncology Unit of Cancer Department of Dakar University

DOI: 10.4236/abcr.2022.111004, PP. 63-68

Keywords: Axillary Dissection, Intercostobrachial Nerve, Pain, Hypoesthesia

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Abstract:

The intercostobrachial nerve (ICBN) is responsible for the sensory innervation of a part of the inner side of the arm. Injury of the intercostobrachial nerve is a complication of axillary dissection during lymph node dissection. Objective: This study aimed to determine the effect of preservation of the intercostobrachial nerve on postoperative sensory disturbances. Methods: This is a prospective, single-center study which was carried out in 90 patients followed in the oncology department of the Aristide Le Dantec hospital in Dakar, suffering from breast cancer and having undergone breast surgery associated with axillary dissection, for a period of 6 months. The patients were divided into two groups depending on whether the intercostobrachial nerve (ICBN) was preserved or not. The two groups were compared in terms of the incidence of sensory disturbances. Results: Sixty patients without nerve preservation and 30 patients with nerve preservation were included in the study, i.e., 90 patients in total. ICBN was injured in 60 patients of which 41 patients (83.7%) developed numbness in the inner arm. While in the preserved group, only 8 patients suffered from numbness (16.3%) with a significant P value of 0.002; however, for other variables such as the incidence of neuropathic pain and hypoesthesia-like sensory

References

[1]  Warrier, S., Hwang, S., Koy, C.E., et al. (2014) Preservation or Division of the Intercostobrachial Nerve in Axillary Dissection for Breast Cancer: Meta-Analysis of Randomised Controlled Trials. The Breast, 1-7.
https://doi.org/10.1016/j.breast.2014.05.020
[2]  Giuliano, A.E., Hunt, K.K., Ballman, K.V. et al. (2011) Axillary Dissection vs No Axillary Dissection in Women with Invasive Breast Cancer and Sentinel Node Metastasis: A Randomized Clinical Trial. Journal of the American Medical Association, 305, 569-575.
https://doi.org/10.1001/jama.2011.90
[3]  Bilimoria, K.Y., Bentrem, D.J., Hansen, N.M. et al. (2009) Comparison of Sentinel Lymph Node Biopsy alone and Completion Axillary Lymph Node Dissection for Node Positive Breast Cancer. Journal of Clinical Oncology, 27, 2946-2953.
https://doi.org/10.1200/JCO.2008.19.5750
[4]  Galimberti, V., Cole, B.F., Zurrida, S., et al. (2013) Axillary Dissection versus No Axillary Dissection in Patients with Sentinel Node Micrometastases (IBCSG 23-01): A Phase 3 Randomized Controlled Trial. The Lancet Oncology, 14, 297-305.
https://doi.org/10.1016/S1470-2045(13)70035-4
[5]  Magnoni, F., Galimberti, V., Corso, G., Intra, M., Sacchini, V. and Veronesi, P. (2020) Axillary Surgery in Breast Cancer: An Updated Historical Perspective. Seminars in Oncology, 47, 341-352.
https://doi.org/10.1053/j.seminoncol.2020.09.001
[6]  Abdullah, T.I., Iddon, J., Barr, L., et al. (1998) Prospective Randomized Controlled Trial of Preservation of the Intercostobrachial Nerve during Axillary Node Clearance for Breast Cancer. British Journal of Surgery, 85, 1443-1145.
https://doi.org/10.1046/j.1365-2168.1998.00843.x
[7]  Taylor, K.O. (2004) Morbidity Associated with Axillary Surgery for Breast Cancer. ANZ Journal of Surgery, 74, 314-317.
https://doi.org/10.1111/j.1445-1433.2004.02992.x
[8]  Torresan, R.Z., Cabello, C., Conde, D.M., et al. (2003) Impact of the Preservation of the Intercostobrachial Nerve in Axillary Lymphadenectomy due to Breast Cancer. The Breast Journal, 9, 389-392.
https://doi.org/10.1046/j.1524-4741.2003.09505.x
[9]  Pereira, S., Fontes, F., Sonin, T., Dias, T., Fragoso, M., Castro-Lopes, J. and Lunet, N. (2017) Neuropathic Pain after Breast Cancer Treatment: Characterization and Risk Factors. Journal of Pain and Symptom Management, 54, 877-888.
https://doi.org/10.1016/j.jpainsymman.2017.04.011
[10]  Macrae, W.A. and Davies, H.T.O. (1999) Chronic Postsurgical Pain. In: Crombie, I.K., Ed., Epidemiology of Pain. Seattle, 125-142.
[11]  Miguel, R., Kunh, A.M., Shons, A.R., et al. (2001) The Effect of Sentinel Node Selective Axillary Lymphadenectomy on the Incidence of Postmastectomy Pain Syndrome. Cancer Control, 8, 427-430.
https://doi.org/10.1177/107327480100800506
[12]  Chirappapha, P., Arunnart, M., Lertsithichai, P., Supsamutchai, C., Sukarayothin, T. and Leesombatpaiboon, M. (2019) Evaluation the Effect of Preserving Intercostobrachial Nerve in Axillary Dissection for Breast Cancer Patient. Gland Surgery, 8, 599-608.
https://doi.org/10.21037/gs.2019.10.06

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