Purpose:The effect of manual lymphatic drainage in patients with breast cancer is
controversial. The purpose of this study is to evaluate the role of manual
lymphatic drainage (MLD) in breast cancer-related lymphedema treatment. Methods: The electronic databases of EMBASE, PubMed, Web of Science, and The Cochrane Library were searched to find English articles
on MLD which were published before January 2020.
After two evaluators selected the studies and independently evaluated
literature quality, meta-analysis was carried out with RevMan 5.3 software. The
outcome index of lymphedema treatment changed in edema
volume. Results: The study includedsix RCTs of 364 patients and
the meta-analysis showed no significant difference in the effect of MLD for
BCRL compared with other treatments (mean difference, 3.76; 95% confidence
interval, -35.09 to 42.62; Z, 0.19; p = 0.850). Conclusion:
References
[1]
Torre, L.A., Islami, F., Siegel, R.L., Ward, E.M. and Jemal, A. (2017) Global Cancer in Women: Burden and Trends. Cancer Epidemiology, Biomarkers & Prevention, 26, 444-457. https://doi.org/10.1158/1055-9965.EPI-16-0858
[2]
DeSantis, C.E., Ma, J.M., Gaudet, M.M., Newman, L.A., Miller, K.D., Sauer, A.G., et al. (2019) Breast Cancer Statistics, 2019. CA: A Cancer Journal for Clinicians, 69, 438-451. https://doi.org/10.3322/caac.21583
[3]
Salonen, P., Rantanen, A., Kellokumpu-Lehtinen, P.L., Huhtala, H. and Kaunonen, M. (2014) The Quality of Life and Social Support in Significant Others of Patients with Breast Cancer—A Longitudinal Study. European Journal of Cancer Care, 23, 274-283. https://doi.org/10.1111/ecc.12153
[4]
Lasinski, B.B., Thrift, K.M., Squire, D., Austin, M.K., Smith, K.M., Wanchai, A., et al. (2012) A Systematic Review of the Evidence for Complete Decongestive Therapy in the Treatment of Lymphedema from 2004 to 2011. PM&R, 4, 580-601.
https://doi.org/10.1016/j.pmrj.2012.05.003
[5]
Asdourian, M.S., Swaroop, M.N., Sayegh, H.E., Brunelle, C.L., Mina, A.I., Zheng, H., et al. (2017) Association between Precautionary Behaviors and Breast Cancer-Related Lymphedema in Patients Undergoing Bilateral Surgery. Journal of Clinical Oncology, 35, 3934-3941. https://doi.org/10.1200/JCO.2017.73.7494
[6]
Huang, T.W., Tseng, S.H., Lin, C.C., Bai, C.H., Chen, C.S., Hung, C.S., et al. (2013) Effects of Manual Lymphatic Drainage on Breast Cancer-Related Lymphedema: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. World Journal of Surgical Oncology, 11, Article No. 15.
https://doi.org/10.1186/1477-7819-11-15
[7]
Shao, Y. and Zhong, D.S. (2017) Manual Lymphatic Drainage for Breast Cancer-Related Lymphoedema. European Journal of Cancer Care, 26, e12517.
https://doi.org/10.1111/ecc.12517
[8]
Andersen, L., Hojris, I., Erlandsen, M. and Andersen, J. (2000) Treatment of Breast-Cancer-Related Lymphedema with or without Manual Lymphatic Drainage—A Randomized Study. Acta Oncologica, 39, 399-405.
https://doi.org/10.1080/028418600750013186
[9]
Dayes, I.S., Whelan, T.J., Julian, J.A., Parpia, S., Pritchard, K.I., D’Souza, D.P., et al. (2013) Randomized Trial of Decongestive Lymphatic Therapy for the Treatment of Lymphedema in Women with Breast Cancer. Journal of Clinical Oncology, 31, 3758-3763. https://doi.org/10.1200/JCO.2012.45.7192
[10]
Gradalski, T., Ochalek, K. and Kurpiewska, J. (2015) Complex Decongestive Lymphatic Therapy with or without Vodder II Manual Lymph Drainage in More Severe Chronic Postmastectomy Upper Limb Lymphedema: A Randomized Noninferiority Prospective Study. Journal of Pain and Symptom Management, 50, 750-757.
https://doi.org/10.1016/j.jpainsymman.2015.06.017
[11]
McNeely, M.L., Magee, D.J., Lees, A.W., Bagnall, K.M., Haykowsky, M. and Hanson, J. (2004) The Addition of Manual Lymph Drainage to Compression Therapy for Breast Cancer Related Lymphedema: A Randomized Controlled Trial. Breast Cancer Research and Treatment, 86, 95-106.
https://doi.org/10.1023/B:BREA.0000032978.67677.9f
[12]
Tambour, M., Holt, M., Speyer, A., Christensen, R. and Gram, B. (2018) Manual Lymphatic Drainage Adds No Further Volume Reduction to Complete Decongestive Therapy on Breast Cancer-Related Lymphoedema: A Multicentre, Randomised, Single-Blind Trial. British Journal of Cancer, 119, 1215-1222.
https://doi.org/10.1038/s41416-018-0306-4
[13]
Williams, A.F., Vadgama, A., Franks, P.J. and Mortimer, P.S. (2002) A Randomized Controlled Crossover Study of Manual Lymphatic Drainage Therapy in Women with Breast Cancer-Related Lymphoedema. European Journal of Cancer Care, 11, 254-261. https://doi.org/10.1046/j.1365-2354.2002.00312.x
[14]
Leduc, O., Leduc, A., Bourgeois, P. and Belgrado, J.P. (1998) The Physical Treatment of Upper Limb Edema. Cancer, 83, 2835-2839.
https://doi.org/10.1002/(SICI)1097-0142(19981215)83:12B+<2835::AID-CNCR36>3.0.CO;2-V
[15]
Eisenhart, A.W., Gaeta, T.J. and Yens, D.P. (2003) Osteopathic Manipulative Treatment in the Emergency Department for Patients with Acute Ankle Injuries. The Journal of the American Osteopathic Association, 103, 417-421.
[16]
Odebiyi, D.O., Aborowa, A.T., Sokunbi, O.G., Aweto, H.A. and Ajekigbe, A.T. (2014) Effects of Exercise and Oedema Massage on Fatigue Level and Quality of Life of Female Breast Cancer Patients. European Journal of Physiotherapy, 16, 238-245.
https://doi.org/10.3109/21679169.2014.959048
[17]
McLaughlin, S.A., DeSnyder, S.M., Klimberg, S., Alatriste, M., Boccardo, F., Smith, M.L., et al. (2017) Considerations for Clinicians in the Diagnosis, Prevention, and Treatment of Breast Cancer-Related Lymphedema, Recommendations from an Expert Panel: Part 2: Preventive and Therapeutic Options. Annals of Surgical Oncology, 24, 2827-2835. https://doi.org/10.1245/s10434-017-5964-6
[18]
Smile, T.D., Tendulkar, R., Schwarz, G., Arthur, D., Grobmyer, S., Valente, S., et al. (2018) A Review of Treatment for Breast Cancer-Related Lymphedema: Paradigms for Clinical Practice. American Journal of Clinical Oncology, 41, 178-190.
https://doi.org/10.1097/COC.0000000000000355
