The multilayer microchannel flow is a promising tool in microchannel-based systems such as hybrid microfluidics. To assist in the efficient design of two-liquid pumping system, a two-fluid electroosmotic flow of immiscible power-law fluids through a microtube is studied with consideration of zeta potential difference near the two-liquid interface. The modified Cauchy momentum equation in cylindrical coordinate governing the two-liquid velocity distributions is solved where both peripheral and inner liquids are represented by power-law model. The two-fluid velocity distribution under the combined interaction of power-law rheological effect and circular wall effect is evaluated at different viscosities and different electroosmotic characters of inner and peripheral power-law fluids. The velocity of inner flow is a function of the viscosities, electric properties and electroosmotic characters of two power-law fluids, while the peripheral flow is majorly influenced by the viscosity, electric property and electroosmotic characters of peripheral fluid. Irrespective of the configuration manner of power-law fluids, the shear thinning fluid is more sensitive to the change of other parameters.
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