全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

Occurrence and Clinical Characteristics of Vaginitis among Women of Reproductive Age in Lagos, Nigeria

DOI: 10.4236/arsci.2022.104009, PP. 91-105

Keywords: Vaginitis, Women, Reproductive Age

Full-Text   Cite this paper   Add to My Lib

Abstract:

Background: Vaginitis is an important public health problem globally. It is?associated with gynaecological and obstetric complications. Vulvovaginal candidiasis,?bacterial vaginosis and trichomoniasis are mainly responsible for vaginitis. The aim of this study is to determine the occurrence, clinical characteristics and associated risk factors of vulvovaginal candidiasis and bacterial vaginosis among women of reproductive age attending Primary Health Care centres in Lagos Nigeria. Methods:This cross-sectional study recruited 258 women with genital complaints after obtaining their informed written consent between May 2017 and March 2018. Structured questionnaires were administered and high vaginal swabs were collected for laboratory examination. The results were analysed with descriptive statistics, chi-square and simple logistic regression. Results: Out of the 210 (81.4%) of the women with one or more vaginal infections, 105 (50.0%), 26 (12.4%) had bacterial vaginosis, and vulvovaginal candidiasis respectively while 78 (37.1%) had both vulvovaginal candidiasis and bacterial vaginosis. Only 1 (0.5%) participant had trichomoniasis and bacterial vaginosis. History of abortion and age below 25 years were associated with vulvovaginal candidiasis while pregnancy, history of miscarriage, age at first sexual activity and discharge were associated with bacterial vaginosis. Itching was associated with both vulvovaginal candidiasis and bacterial vaginosis. Conclusion: This study revealed vulvovaginal candidiasis and bacterial vaginosis as important cause of genital complaints among reproductive

References

[1]  World Health Organization (2021) Sexually Transmitted Infections (STIs). Key Facts. World Health Organization, Geneva.
[2]  World Health Organization (2013) Report on Global Sexually Transmitted Infection Surveillance. World Health Organization, Geneva.
[3]  Majigo, M.V., Kashindye, P., Mtulo, Z. and Joachim, A. (2021) Bacterial Vaginosis, the Leading Cause of Genital Discharge among Women Presenting with Vaginal Infection in Dares Salaam, Tanzania. African Health Sciences, 21, 531-537.
https://doi.org/10.4314/ahs.v21i2.7
[4]  Mulu, W., Yimer, M., Zenebe, Y. and Abera, B. (2015) Common Causes of Vaginal Infections and Antibiotic Susceptibility of Aerobic Bacterial Isolates in Women of Reproductive Age Attending at Felegehiwot Referral Hospital , Ethiopia: A Cross Sectional Study. BMC Women’s Health, 15, Article No. 42.
https://doi.org/10.1186/s12905-015-0197-y
[5]  Narayankhedkar, A., Hodiwala, A. and Mane, A. (2015) Clinicoetiological Characterization of Infectious Vaginitis amongst Women of Reproductive Age Group from Navi Mumbai, India. Journal of Sexually Transmitted Diseases, 2015, Article ID: 817092.
https://doi.org/10.1155/2015/817092
[6]  Mascarenhas, R.E.M., Machado, M.S.C., Borges da Costa e Silva, B.F., Pimentel, R.F.W., Ferreira, T.T., Leoni, F.M.S. and Grassi, M.F.R. (2012) Prevalence and Risk Factors for Bacterial Vaginosis and Other Vulvovaginitis in a Population of Sexually Active Adolescents from Salvador, Bahia, Brazil. Infectious Diseases in Obstetrics and Gynecology, 2012, Article ID: 378640.
https://doi.org/10.1155/2012/378640
[7]  Abdul-Aziz, M., Mahdy, A.K., Abdul-Ghani, R., Alhilali, N.A., Al-Mujahed, L.K.A., Alabsi, S.A., Al-Shawish, F.A.M., Alsarari, N.J.M., Bamashmos, W., Abdulwali, S.J.H., Al Karawani, M. and Almikhlafy, A.A. (2019) Bacterial vaginosis, Vulvovaginal candidiasis and Trichomonal vaginitis among Reproductive-Aged Women Seeking Primary Healthcare in Sana’a City, Yemen. BMC Infectious Diseases, 19, Article No. 879.
https://doi.org/10.1186/s12879-019-4549-3
[8]  Zullo, M.A., Schiavi, M.C., Di Pinto, A., Prata, G., Scudo, M., Luffarelli, P. and Oliva, C. (2020) Efficacy and Safety of Oral Administration of a Product Based on Hydroxytyrosol as Preventive Therapy for Recurrent Vulvo-Vaginal Candidosis: A Prospective Observational Pilot Study. European Review for Medical and Pharmacological Sciences, 24, 7427–7432.
[9]  Arastehfar, A., Kargar, M.L., Mohammadi, S.R., Roudbary, M., Ghods, N., Haghighi, L., Daneshnia, F., Tavakoli, M., Jafarzadeh, J., Hedayati, M.T., Wang, H., Fang, W., Carvalho, A., Llkit, M., Perlin, D.S. and Lass-Florl, C. (2021) A High Rate of Recurrent Vulvovaginal Candidiasis and Therapeutic Failure of Azole Derivatives among Iranian Women. Frontiers in Microbiology, 12, Article ID: 655069.
https://doi.org/10.3389/fmicb.2021.655069
[10]  Hedayati, M.T., Taheri, Z., Galinimoghadam, T., Aghili SR Cherati, J.Y. and Mosayebi, E. (2015) Isolation of Different Species of Candida in Patients with Vulvovaginal Candidiasis from Sari Iran. Jundishapur Journal of Microbiology, 8, Article ID: e15992.
https://doi.org/10.5812/jjm.8(4)2015.15992
[11]  Nwadioha, S.I., Egah, D.Z., Alao, O.O., Iheanacho, E. (2010) Risk Factors for Vaginal Candidiasis among Women Attending Primary Health Care Centres of Jos Nigeria. Journal of Clinical Medicine and Research, 2, 110-113.
[12]  Sule-Odu, A.O., Akadri, A.A., Oluwole, A.A., Osinupebi, O.A., Andu, B.A., Akiseku, A.K. and Lawal, A.I. (2020) Vaginal Candida Infection in Pregnancy and Its Implications for Fetal Well-Being. African Journal of Reproductive Health, 24, 33-40.
[13]  Chavoustie, S.E., Eder, S.E., Koltun, W.D., Lemon, T.R., Mitchell, C., Nyirjesy, P., Sobel, J.D., Sobel, R. and Villanueva, R. (2017) Experts Explore the State of Bacterial Vaginosis and the Unmet Needs Facing Women and Providers. International Journal of Gynecology & Obstetrics, 137, 107-109.
https://doi.org/10.1002/ijgo.12114
[14]  Klebanoff, M.A., Schwebke, J.R., Zhang, J., Nansel, T.R., Yu, K.F. and Andrews, W.W. (2004) Vulvovaginal Symptoms in Women with Bacterial Vaginosis. Obstetrics & Gynecology, 104, 267-272.
https://doi.org/10.1097/01.AOG.0000134783.98382.b0
[15]  Bilardi, J., Walker, S., Mooney-Somers, J., Temple-Smith, M., McNair, R., Bellhouse, C., Fairley, C., Chen, M. and Bradshaw, C. (2016) Women’s Management of Recurrent Bacterial Vaginosis and Experiences of Clinical Care: A Qualitative Study. PLOS ONE, 11, Article ID: e0151794.
https://doi.org/10.1371/journal.pone.0151794
[16]  Kissinger, P. (2015) Trichomonas vaginalis: A Review of Epidemiologic, Clinical and Treatment Issues. BMC Infectious Diseases, 15, Article No. 307.
https://doi.org/10.1186/s12879-015-1055-0
[17]  Arbabi, M., Delavari, M., Fakhrieh-Rashan, Z. and Hooshyar, H. (2018). Review of Trichomonas vaginalis in Iran Based on Epidemiological Situation. Journal of Reproduction & Infertility, 19, 82-88.
[18]  Idakwo, J., Yaro, C.A., Akoh, Q.P. and Raji, R.O. (2020) A Study of Trichomonas vaginalis and Risk Factors in Women of Reproductive Age Attending Health Facilities in Okene Metropolis, Kogi State, Nigeria. Journal of Clinical and Scientific Research, 9, 213-217.
[19]  Enitan, S.S., Ihongbe, J.C., Ochei, J.O., Otuneme, G.O., Itodo, G.E. and Kalejaiye, O.S. (2018) Prevalence of Bacterial Vaginosis and Associated Risk Factors among Non-Pregnant Women in Ilara Community of Ogun State, Nigeria. International Journal of Public Health Research, 6, 35-46.
[20]  Abdullateef, R.M., Ijaiya, M.A., Abayomi, F., Adeniran, A.S. and Idris, H. (2017) Bacterial Vaginosis: Prevalence and Associated Risk Factors among Non-Pregnant Women of Reproductive Age Attending a Nigerian Tertiary Hospital. Malawi Medical Journal, 29, 290-293.
https://doi.org/10.4314/mmj.v29i4.2
[21]  Edet, U.O., Mboto, C.I., Mbim, E.N., George, U.E., Umego, C.F. and Okon, J. (2017) Prevalence of Bacterial Vaginosis amongst Female Students of the University of Calabar, Calabar, Cross River State. Asian Journal of Research in Medical and Pharmaceutical Sciences, 2, 1-8.
https://doi.org/10.9734/AJRIMPS/2017/36127
[22]  Wariso, K.T., Oboro, I.L. and Igumna, J.A. (2017) Prevalence and Clinical Manifestations of Candidiasis among Patients with Vulvovaginitis in a Tertiary Institution in Southern Nigeria. Cross River Journal of Medicine, 1, 10-17.
[23]  Cheesbrough, M. (2000) District Laboratory Practice in Tropical Countries Part 2. Cambridge University Press, Cambridge, 38, 92, 244.
[24]  Olowe, O.A., Makanjuola, O.B., Olowe, R. and Adekanle, D.A. (2014) Prevalence of Vulvovaginal candidiasis, Trichomoniasis and Bacterial vaginosis among Pregnant Women Receiving Antenatal Care in South Western Nigeria. European Journal of Microbiology and Immunology, 4, 193-197.
https://doi.org/10.1556/EUJMI-D-14-00027
[25]  Konadu, D.G., Owusu-Ofori, A., Yidana, Z., Boadu, F., Iddrisu, L.F., Adu-Gyasi, D., Dosoo, D., Awuley, R.L., Owusu-Agyei, S. and Asante, K.P. (2019) Prevalence of Vulvovaginal candidiasis, Bacterial vaginosis and Trichomoniasis in Pregnant Women Attending Antenatal Clinic in the Middle Belt of Ghana. BMC Pregnancy and Childbirth, 19, Article No. 341.
https://doi.org/10.1186/s12884-019-2488-z
[26]  Payne, V.K., Cécile, T.T.F., Cedric, Y., Nadia, N.A.C. and Jose, O. (2020) Risk Factors Associated with Prevalence of Candida albicans, Gardnerella vaginalis, and Trichomonas vaginalis among Women at the District Hospital of Dschang, West Region, Cameroon. International Journal of Microbiology, 2020, Article ID: 8841709.
https://doi.org/10.1155/2020/8841709
[27]  Gupta, R.S., Bhargav, D. and Deep, J.P. (2021) Common Types of Vaginitis (Bacterial vaginosis, Vulvovaginal candidiasis, Trichomoniasis) and Their Association with Urinary Tract Infection among Women Visiting NMCTH, Birgunj. International Journal of Current Microbiology and Applied Sciences, 10, 996-1010.
https://doi.org/10.20546/ijcmas.2021.1001.121
[28]  Kadir, M.A., Sulymaz, M.A., Dawood, I.S. Cambridge Shams-Eldin, S. (2014) Trichomonas Vaginalis and Associated Microorganisms in Women with Vaginal Discharge in Kerkuk-Iraq. Ankara Medical Journal, 14, 91-99.
[29]  Masand, D.L., Patel, J. and Gupta, S. (2015) Utility of Microbiological Profile of Symptomatic Vaginal Discharge in Rural Women of Reproductive Age Group. Journal of Clinical and Diagnostic Research, 9, QC04-QC07.
https://doi.org/10.7860/JCDR/2015/12161.5623
[30]  Swaminathan, K.R., Devi, M., Gerald, S., Prakesh, S.C. and Thomas, B.M. (2017) Prevalence of Vulvovaginal Candidiasis in the Women of the Reproductive Age in Rural India. International Journal of Clinical Obstetrics and Gynaecology, 1, 37-39.
[31]  Makanjuola, O., Adedokun, B., Fayemiwo, S. and Bakare, R. (2016) Correlates of Vulvovaginal Candidiasis among Attendees of a Special Treatment Clinic in Nigeria. International STD Research & Reviews, 4, 1-7.
https://doi.org/10.9734/ISRR/2016/27811
[32]  Emeribe, A.U., Nasir, I.A., Onyia, J. and Ifunanya, A.L. (2015) Prevalence of Vulvovaginal Candidiasis among Non Pregnant Women Attending Tertiary Health Care Facility in Abuja Nigeria. Research and Reports in Tropical Medicine, 6, 37-42.
https://doi.org/10.2147/RRTM.S82984
[33]  Akafyi, D.E., Oko, J.O., Umar, M., Obafemi, A. and Michael, R. (2016) Prevalence of Bacterial, Trichomonas and Candidal Vaginosis among Females in Angwan-Fulani, Palladan in Zaria, Nigeria. Journal of Applied Life Sciences International, 5, 1-6.
https://doi.org/10.9734/JALSI/2016/25649
[34]  Pondei, K., Jeremiah, I., Lawani, E. and Nsikak, E. (2017) The Prevalence of Symptomatic Vulvovaginal Candidiasis and Trichomonas Vaginalis Infection and Associated Risk Factors among Women in the Niger Delta Region of Nigeria. International STD Research & Reviews, 5, 1-10.
https://doi.org/10.9734/ISRR/2017/32057
[35]  Uzoh, C.V., Iheukwumere, I.H., Umezuruike, K.C. and Onyewenjo, S.C. (2017) Prevalence of Candida Albicans among Women Attending Federal Medical Centre Asaba, Delta State, Nigeria. International Journal of Biochemistry and Biotechnology, 6, 735-739.
[36]  Sahoo, S., Mohanty, I., Parida, B. and Patnaik, S. (2018) Prevalence of Vulvovaginal Candidiasis in Sexually Active Females with Antifungal Susceptibility Patterns of the Isolates. International Journal of Clinical and Biomedical Research, 4, 38-41.
[37]  Aalei, B.S.H. and Touhidi, A. (2000) Prevalence of Candida Vaginitis among Symptomatic Patients in Kerman. The Journal of Qazvin University of Medical Sciences, 4, 42-48.
[38]  Ibrahim, S.M., Bukar, M., Mohammed, Y., Audu, B.M. and Ibrahim, H.M. (2013) Prevalence of Vaginal Candidiasis among Pregnant Women with Abnormal Vaginal Discharge in Maiduguri. Nigerian Journal of Medicine, 22, 138-142.
[39]  Mucci, M.J., Cuestas, M.L., Landanburu, M.F. and Mujica, M.T. (2017) Prevalence of Candida albicans, Candida dubliniensis and Candida africana in Pregnant Women Suffering from Vulvovaginal Candidiasis in Argentina. Revista Iberoamericana de Micología, 34, 72-76.
https://doi.org/10.1016/j.riam.2016.09.001
[40]  Sangare, I., Sirima, C., Bamba, S., ZidaA, Cissé, M., Bazié, W.W., Sanou, S., Dao, B., Menan, H. and Guiguemdé, R.T. (2018) Prevalence of Vulvovaginal Candidiasis in Pregnancy at Three Health Centers in Burkina Faso. Journal de Mycologie Médicale, 28, 186-192
https://doi.org/10.1016/j.mycmed.2017.08.006
[41]  Akinbami, N.A., Babalola, G.O., Shittu, M.O., Tijani, A.M. and Adekola, S.A. (2015) Detection and Epidemiology of Vulvovaginal Candidiasis among Asymptomatic Pregnant Women Attending a Tertiary Hospital in Ogbomoso, Nigeria. International Journal of Biomedical Research, 6, 518-523.
https://doi.org/10.7439/ijbr.v6i7.2242
[42]  Abdelaziz, Z.A., Ibrahim, M.E., Bilal, N.E. and Hamid, M.E. (2014) Vaginal Infections among Pregnant Women at Omdurman Maternity Hospital in Khartoum, Sudan. The Journal of Infection in Developing Countries, 8, 490-497.
https://doi.org/10.3855/jidc.3197
[43]  Bonneton, M., Huynh, B., Seck, A., Bercion, R., Sarr, F.D., Delarocque-Astagneau, E. and Vray, M. (2021) Bacterial Vaginosis and Other Infections in Pregnant Women in Senegal. BMC Infectious Diseases, 21, Article No. 1090.
https://doi.org/10.1186/s12879-021-06767-4
[44]  Udenze, C.L., Achi, O.K., Obeagu, E.I. and Elemchukwu, Q. (2014) Prevalence of bacterial Vaginosis among Female Students of Michael Okpara University of Agriculture Umudike, Abia State, Nigeria. IOSR Journal of Pharmacy and Biological Sciences, 9, 39-52.
https://doi.org/10.9790/3008-09523952
[45]  Nagajothi, A. and Muthulakshmi, K. (2018). Prevalence of Trichomonas vaginalis Using Parasitological Methods in Kanchipuram. International Journal of Scientific Research, 7, 63-64.
[46]  Okonko, I.O., Akinpelu, A.O. and Okerentugba, P.O. (2012) Prevalence of Sexually Transmitted Infections (STIs) among Attendees of AFRH Centre in Ibadan, Southwestern Nigeria. Middle-East J Scientific Research, 11, 24-31.
[47]  Tine, R.C., Sylla, K., Ka, R., Dia, L., Sow, D., Lelo, S., Diallo, K., Faye, B., Dieng, T., Ndour, C.T. and Sow, A.Y. (2019) A Study of Trichomonas vaginalis Infection and Correlates in Women with Vaginal Discharge Referred at Fann Teaching Hospital in Senegal. Journal of Parasitology Research, 2019, Article ID: 2069672.
https://doi.org/10.1155/2019/2069672
[48]  Mahmoud, A., Sherif, N.A., Abdella, R., El-Genedy, A.R., El Kateb, A.Y. and Askalani, A.N. (2015) Prevalence of Trichomonas vaginalis Infection among Egyptian Women Using Culture and Latex Agglutination: Cross-Sectional Study. BMC Women’s Health, 15, Article No. 7.
https://doi.org/10.1186/s12905-015-0169-2
[49]  Azambakhtiar, A., Nikmanesh, B., Rezaeian, M., Dashti, N., Safari, F. and Zarebavani, M. (2018) The Prevalence of Trichomoniasis in Women Referred to Clinical Centers in South of Tehran, Iran during 2015-2016. Iranian Journal of Parasitology, 13, 108-113.
[50]  Adjei, C., Boateng, R., Dompreh, A., Okyere, B. and Owiredu, E. (2019) Prevalence and the Evaluation of Culture, Wet Mount, and ELISA Methods for the Diagnosis of Trichomonas vaginalis Infection among Ghanaian Women Using Urine and Vaginal Specimens. Tropical Medicine and Health, 47, Article No. 33.
https://doi.org/10.1186/s41182-019-0162-9
[51]  Squire, D.S., Lymbery, A.J., Walters, J., Ahmed, H., Asmah, R.H., Thompson, R.C.A. (2019) Trichomonas vaginalis Infection in Southern Ghana: Clinical Signs Associated with the Infection. Transactions of the Royal Society of Tropical Medicine and Hygiene, 113, 359-369.
https://doi.org/10.1093/trstmh/trz019
[52]  Ranjit, E., Raghubanshi, B.R., Maskey, S. and Pramila, P. (2018) Prevalence of Bacterial Vaginosis and Its Association with Risk Factors among Non-Pregnant Women: A Hospital Based Study. International Journal of Microbiology, 2018, Article ID: 8349601.
https://doi.org/10.1155/2018/8349601
[53]  Garba, D.J., Zabaze, S.S., Tabitha, S., James, G. and Makshwar, K. (2014) Microbiological Diagnosis of Bacterial Vaginosis in Pregnant Women in a Resource Limited Setting in North Central Nigeria. American Journal of Life Sciences, 2, 356-360.
https://doi.org/10.11648/j.ajls.20140206.15
[54]  Karmastaji, A., Khajeh, F.G.H. and Amirian, M. (2005) Comparison between Clinical and Laboratory Diagnosis of Vaginitis. Hormozgan Medical Journal, 9, 131-136.
[55]  Habibipour, R. (2016) Prevalence Rate of Vulvovaginal Candidiasis and Identification of Candida Species in Women Referred to Hamedan Hospitals 2013-2014, West of Iran. Zahedan Journal of Research in Medical Sciences, 18, Article No. e6250.
https://doi.org/10.17795/zjrms-6250
[56]  Apalata, T., Nojaholo, S., Seipone, I.D. and Nxasana, N. (2021) Characterizations of Bacterial Vaginosis among HIV Positive and HIV Negative Women in Rural Eastern Cape Province, South Africa. International Journal of Microbiology, 2021, Article ID: 9913878.
https://doi.org/10.1155/2021/9913878

Full-Text

comments powered by Disqus

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133

WeChat 1538708413