全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

An Eight-Year Review of the Frequency and Outcome of Dog Bite and Clinical Rabies in a Teaching Hospital in North Central Nigeria

DOI: 10.4236/wjns.2022.124021, PP. 203-215

Keywords: Dog Bite, Rabies Virus Infection, Makurdi, North Central, Nigeria

Full-Text   Cite this paper   Add to My Lib

Abstract:

Introduction: Rabies is a neglected tropical disease that is highly fatal and yet it is under-reported in the developing countries like Nigeria. The domestic dog is the primary reservoir host as well as the most important source of infection usually conveyed by saliva through bites. Aim: This study sought to determine the frequency and outcome of dog bite injury and clinical rabies presented to the Accident and Emergency unit of Benue State University Teaching Hospital Makurdi, Benue State, Nigeria. Methods: This retrospective hospital-based study reviewed the medical records of all patients with dog bite who presented over an eight-year period from August 2014 to July 2022. Rabies virus infection was diagnosed on clinical basis. A structured proforma was used to extract relevant information and data was analysed using the statistical package for social sciences (SPSS) version 21. Result: Mean and median age was 27.03 ± 10.98 and 29 years respectively, range of 2 - 47 years and 11 (73.3%) were males. There were 15 cases of dog bite out of 17,187 patients making frequency of 1.14 per 1000 persons constituting 0.09% or about 2 cases yearly. Seven (46.7%) of this total number had clinical rabies infection with 7 (100.0%) mortality. All 7 (100.0%) with clinical rabies had a furious (encephalitic) form. Rabies immunoglobulin was prescribed in 8 (53.3%), 6 (40.0%) received them while 13 (86.7%) received post-exposure rabies vaccine. Conclusion: Dog bite is an uncommon reason for Accident and Emergency visit in our facility with male preponderance. However, about 46.7% of the dog bite victims developed clinical symptoms suggestive of furious (encephalitic) form of rabies with 100.0% fatality.

References

[1]  Hampson, K., Coudeville, L., Lembo, T., et al. (2015) Estimating the Global Burden of Endemic Canine Rabies. PLOS Neglected Tropical Diseases, 9, e0003709.
https://doi.org/10.1371/journal.pntd.0003709
[2]  Hagos, W.G., Muchie, K.F., Gebru, G.G., Mezgebe, G.G., Reda, K.A. and Dachew, B.A. (2020) Assessment of Knowledge, Attitude and Practice towards Rabies and Associated Factors among Household Heads in Mekelle City, Ethiopia. BMC Public Health, 20, Article No. 57.
https://doi.org/10.1186/s12889-020-8145-7
[3]  Singh, R., Singh, K.P., Cherian, S., Saminathan, M., Kapoor, S., Manjunatha Reddy, G.B., et al. (2017) Rabies—Epidemiology, Pathogenesis, Public Health Concerns and Advances in Diagnosis and Control: A Comprehensive Review. Veterinary Quarterly, 37, 212-251.
https://doi.org/10.1080/01652176.2017.1343516
[4]  Cleaveland, S. (1998) Epidemiology and Control of Rabies: The Growing Problem of Rabies in Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene, 92, 131-134.
https://doi.org/10.1016/S0035-9203(98)90718-0
[5]  Rupprecht, C.E., Hanlon, C.A. and Hemachudha, T. (2002) Rabies Re-Examined. The Lancet Infectious Diseases, 2, 327-343.
https://doi.org/10.1016/S1473-3099(02)00287-6
[6]  Centers for Disease Control and Prevention (2004) Investigation of Rabies Infections in Organ Donor and Transplant Recipients—Alabama, Arkansas, Oklahoma, and Texas, 2004. Morbidity and Mortality Weekly Report, 53, 586-589.
[7]  Srinivasan, A., Burton, E.C., Kuehnert, M.J., et al. (2005) Transmission of Rabies Virus from an Organ Donor to Four Transplant Recipients. The New England Journal of Medicine, 352, 1103-1111.
https://doi.org/10.1056/NEJMoa043018
[8]  Centers for Disease Control and Prevention (2013) CDC Confirms Rabies Death in Organ Transplant Recipient. CDC Newsroom.
https://www.cdc.gov/media/releases/2013/s0315_rabies_organs.html
[9]  Liu, C. and Cahill, J.D. (2013) Epidemiology of Rabies and Current US Vaccine Guidelines. Rhode Island Medical Journal, 103, 51-53.
[10]  Gompf, S.G. and Pham, T.M. (2022) Medscape. Rabies Clinical Presentation.
https://emedicine.medscape.com/article/220967-clinical
[11]  World Health Organization (2015) Rabies: Rationale for Investing in the Global Elimination of Dog-Mediated Human Rabies.
https://apps.who.int/iris/handle/10665/185195
[12]  Knobel, D.L., Cleaveland, S., Coleman, P.G., et al. (2005) Re-Evaluating the Burden of Rabies in Africa and Asia. Bulletin of the World Health Organization, 83, 360-368.
[13]  Mshelbwala, P.P., Weese, J.S., Sanni-Adeniyi, O.A., Chakma, S., Okeme, S.S., Mamun, A.A., Rupprecht, C.E. and Magalhaes, R.J.S. (2021) Rabies Epidemiology, Prevention and Control in Nigeria: Scoping Progress towards Elimination. PLOS Neglected Tropical Diseases, 15, e0009617.
https://doi.org/10.1371/journal.pntd.0009617
[14]  Omoke, N.I. and Chukwueloka Onyemaechi, N.O. (2018) Incidence and Pattern of Dog Bite Injuries Treated in the Emergency Room of a Teaching Hospital South East Nigeria. African Journal of Medical and Health Sciences, 17, 35-40.
[15]  Abubakar, S.A. and Bakari, A.G. (2012) Incidence of Dog Bite Injuries and Clinical Rabies in a Tertiary Health Care Institution: A 10-Year Retrospective Study. Annals of African Medicine, 11, 108-111.
https://doi.org/10.4103/1596-3519.93534
https://www.annalsafrmed.org/text.asp?2012/11/2/108/93534
[16]  Ogundare, E.O., Olatunya, O.S., Oluwayemi, I.O., Inubile, A.J., Taiwo, A.B., Agaja, O.T., Airemionkhale, A. and Fabunmi, A. (2017) Pattern and Outcome of Dog Bite Injuries among Children in Ado-Ekiti, Southwest Nigeria. Pan African Medical Journal, 27, Article 81.
https://doi.org/10.11604/pamj.2017.27.81.7360
[17]  Tialla, D. (2021) Rabies Virus in Biting Dogs and Behaviour at Risk of Zoonotic Transmission of Rabies in Ouagadougou, Burkina Faso. African Journal of Microbiology Research, 15, 490-496.
https://doi.org/10.5897/AJMR2021.9575
[18]  Punguyire, D.T., Osei-Tutu, A., Aleser, E.V. and Letsa, T. (2017) Level and Pattern of Human Rabies and Dog Bites in Techiman Municipality in the Middle Belt of Ghana: A Six Year Retrospective Records Review. Pan African Medical Journal, 28, Article 281.
https://doi.org/10.11604/pamj.2017.28.281.14218
[19]  Desa, G., Birasa, D., Deneke, Y. and Oljira, D. (2020) Assessment of Knowledge, Attitude and Practice (KAP) of Community toward Rabies in Medawelabu District, Bale Zone, Ethiopia. International Journal of Research-GRANTHAALAYAH, 8, 29-42.
https://doi.org/10.29121/granthaalayah.v8.i3.2020.124
[20]  Dodet, B., Tejiokem, M.C., Aguemon, A.-R. and Bourhy, H. (2015) Human Rabies Deaths in Africa: Breaking the Cycle of Indifference. International Health, 7, 4-6.
https://doi.org/10.1093/inthealth/ihu071
[21]  Adesina, M.A., Olufadewa, I.I., Ogah, Y.I. and Nwachukwu, N. (2020) Incidence and Mortality from a Neglected Tropical Disease (Rabies) in 28 African Countries. Folia Veterinaria, 64, 46-51.
https://doi.org/10.2478/fv-2020-0016
[22]  World Health Organization (2021) Rabies.
https://www.who.int/news-room/fact-sheets/detail/rabies
[23]  Yizengaw, E., Getahun, T., Mulu, W., et al. (2018) Incidence of Human Rabies Virus Exposure in Northwestern Amhara, Ethiopia. BMC Infectious Diseases, 18, Article No. 597.
https://doi.org/10.1186/s12879-018-3500-3
[24]  Yibrah, M. and Damtie, D. (2015) Incidence of Human Rabies Exposure and Associated Factors at the Gondar Health Center, Ethiopia: A Three-Year Retrospective Study. Infectious Diseases of Poverty, 4, Article No. 3.
https://doi.org/10.1186/2049-9957-4-3
[25]  Onyemocho, A., Moses, A., Kisani, A., Victoria, O.N. and Joseph, A. (2020) Assessment of Knowledge and Practice of Vaccination of Dogs against Rabies by Dog Owners in Makurdi, Benue State, Nigeria. Annals of Medical Research and Practice, 1, 1:5.
https://doi.org/10.25259/ANMRP_1_2020
[26]  World Health Organization (2018) Rabies Vaccines and Immunoglobulins: WHO Position.
https://apps.who.int/iris/bitstream/handle/10665/259855/WHO-CDS-NTD-NZD-2018.04-eng.pdf?sequence=1

Full-Text

Contact Us

[email protected]

QQ:3279437679

WhatsApp +8615387084133