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核磁共振波谱仪在综合性有机化学实验中的应用
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Abstract:
核磁共振波谱仪是一种可快速确定有机化合物结构的大型仪器设备。本文介绍了核磁共振波谱仪在新疆开放共享的现状，并以交叉脱氢偶联反应合成色酮并[2,3-c]吡唑-4(1H)-酮为例将核磁共振波谱仪应用于综合性有机化学实验，对于提高学生学习有机化学的兴趣、提升学生开展实验的综合技能、培养学生的科研创新意识和能力具有重要作用。同时，也可以增加核磁共振波谱仪的使用效率，促进科研反哺教学。
The Nuclear Magnetic Resonance (NMR) spectrometer is a large-scale instrument and equipment which can quickly verify the structure of organic compounds. This paper described the present situation of open and shared NMR spectrometers in Xinjiang. Taking the synthesis of chromeno[2,3-c]pyrazol-4(1H)-one through cross-dehydrogenative coupling reaction as an example, the application of NMR spectrometer in comprehensive organic chemistry experiment played an important role in improving students’ interest in learning organic chemistry, promoting students’ comprehensive skills in carrying out experiments, and cultivating students’ consciousness and ability of scientific research and innovation. Meanwhile, it could also increase the utilization rate of NMR spectrometer, and promote scientific research to feed teaching.
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| [2] | 田忠贞, 李冬梅. 综合性有机化学实验的设计与探索[J]. 山东化工, 2021, 50(8): 217-218. |
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https://doi.org/10.3390/molecules15096106 |
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https://doi.org/10.1081/SCC-120030741 |
