Objective: Through this surgical series, we present the epidemiological and anatomical-clinical
aspects and the surgical results concerning patients operated on for a primary cardiac
tumor at the Abidjan Heart Institute.Materials
and Method:This is a retrospective descriptive
study covering the period of January 1982 to December 2022, based on the medical
records of patients operated on for a primary cardiac tumor at the Abidjan Heart
Institute. Results: Twenty-seven (27) patients underwent surgery for a primary cardiac tumor,
including 14 women and 13 men with a mean age of 41.5 years (range 19-76 years). The main circumstances of discovery were exertional
dyspnea, palpitation and syncope or pseudo-syncope. The main site was the septal
wall of the left atrium. The diagnosis of myxoma was confirmed by pathological examination
of the surgical specimen in 96.3% (n=24) of the
patients and it was a malignant large cell immunoblastic lymphoma of the myocardium
in 3.7% (n=1) of the patients. The mean
largest diameter was 46.1mm. The
postoperative course was marked by an ischaemic stroke (n=1); recurrence of a left atrial myxoma 5 years after
the first tumor removal (n=1).
References
[1]
Rahouma, M., Arisha, M.J., Elmously, A., El-Sayed Ahmed, M.M., Spadaccio, C., Mehta, K., et al. (2020) Cardiac Tumors Prevalence and Mortality: A Systematic Review and Meta-Analysis. International Journal of Surgery, 76, 178-189. https://doi.org/10.1016/j.ijsu.2020.02.039
[2]
Castello, J. and Silvay, G. (2010) Characterization and Management of Cardiac Tumors. Seminars in Cardiothoracic and Vascular Anesthesia, 14, 6-20. https://doi.org/10.1177/1089253210362596
[3]
Burazor, I., Aviel-Ronen, S., Imazio, M., Markel, G., Grossman, Y., Yosepovich, A., et al. (2014) Primary Malignancies of the Heart and Pericardium. Clinical Cardiology, 37, 582-588. https://doi.org/10.1002/clc.22295
[4]
Reynen, K. (1995) Medical Progress: Cardiac Myxomas. New England Journal of Medicine, 333, 1610-1617. https://doi.org/10.1056/NEJM199512143332407
[5]
Elbardissi, A.W., Dearani, J.A., Daly, R.C., Mullany, C.J., Orszulak, T.A., Puga, F.J., et al. (2008) Survival after Resection of Primary Cardiac Tumors: A 48-Year Experience. Circulation, 118, S7-S15. https://doi.org/10.1161/CIRCULATIONAHA.107.783126
[6]
Khakural, P., Baral, R., Bhattarai, A. and Koirala, B. (2022) Cardiac Myxoma among Patients Undergoing Cardiac Surgery in a Tertiary Care Center: A Descriptive Cross-Sectional Study. Journal of Nepal Medical Association, 60, 111-115. https://doi.org/10.31729/jnma.6538
[7]
Reardon, M.J. and Smythe, W.R. (2003) Cardiac Neoplasms. In: Cohn, L.H. and Edmunds Jr., L.H., Eds., Cardiac Surgery in the Adult, McGraw-Hill, New York, 1373-400.
[8]
Lam, K.Y., Dickens, P. and Chan, A.C. (1993) Tumors of the Heart. A 20-Year Experience with a Review of 12,485 Consecutive Autopsies. Archives of Pathology and Laboratory Medicine, 117, 1027-1031.
[9]
Yoon, J.-H., Kim, J.-H., Sung, Y.-J., Lee, M.-H., Cha, M.-J., Kang, D.-Y., Kim, Y.-J. and Ahn H (2011) Cardiac Myxoma Originating from the Anterior Mitral Valve Leaflet. Journal of Cardiovascular Ultrasound, 19, 228-231. https://doi.org/10.4250/jcu.2011.19.4.228
[10]
Bouferrouk, A. and Boutamine, S. (2011) Left Ventricular Myxoma. Sang Thrombose Vaisseaux, 23, 317-319.
[11]
Francois, J., Kupferstein, E., Abdul, R., Casillas, J., Ibtida, I., Salifu, M. and McFarlane, S.I. (2020) Asymptomatic Patient with an Uncommonly Located Myxoma in the Left Ventricle Attached to Chordae Tendinae. American Journal of Medical Case Reports, 8, 313-314. https://doi.org/10.12691/ajmcr-8-9-14
[12]
Butany, J., Leong, S.W., Carmichael, K. and Komeda, M. (2005) A 30-Year Analysis of Cardiac Neoplasms at Autopsy. Canadian Journal of Cardiology, 21, 675-680.
[13]
Butany, J., Nair, V., Naseemuddin, A., Nair, G.M., Catton, C. and Yau, T. (2005) Cardiac Tumors: Diagnosis and Management. Lancet Oncology, 6, 219-28. https://doi.org/10.1016/S1470-2045(05)70093-0
[14]
Yilmaz, M., Gurlertop, Y., Kocaturk, H., Karakelleoglu, S. and Kocak, H. (2004) Unusually Large Left Atrial Myxoma Presenting with Severe Mitral Valve Obstruction Symptoms. Echocardiography, 21, 145-148. https://doi.org/10.1111/j.0742-2822.2004.03089.x
[15]
Saaf, S., Miqdadi, A., Merzouk, F.-Z., El Aidaoui, K. and Hazim, A. (2022) Cardiac Myxoma as a Rare Cause of an Ischemic Stroke of the Vertebrobasilar Territory in a Young Adult: A Case Report. Cureus, 14, e24792. https://doi.org/10.7759/cureus.24792
[16]
Sato, H., Tanaka, T., Kasai, K., Kita, T. and Tanaka, N. (2008) Sudden Death Due to Acute Pulmonary Embolism from Asymptomatic Right Atrial Myxoma. Journal of Forensic Legal Medicine, 2, 10-13. https://doi.org/10.1016/j.jflm.2008.02.013
[17]
Ragland, M.M. and Tak, T. (2006) The Role of Echocardiography in Diagnosing Space-Occupying Lesions of the Heart. Clinical Medicine and Research, 4, 22-32. https://doi.org/10.3121/cmr.4.1.22
[18]
Luna, A., Ribes, R., Caro, P., Vida, J. and Erasmus, J.J. (2005) Evaluation of Cardiac Tumors with Magnetic Resonance Imaging. European Radiology, 15, 1446-1455. https://doi.org/10.1007/s00330-004-2603-y
[19]
Shenoy, C., Grizzard, J.D., Shah, D.J., Kassi, M., Reardon, M.J., Zagurovskaya, M., Kim, H.W., Parker, M.A. and Kim, R.J. (2021) Cardiovascular Magnetic Resonance Imaging in Suspected Cardiac Tumor: A Multicentre Outcomes Study. European Heart Journal, 43, 71-80. https://doi.org/10.1093/eurheartj/ehab635
[20]
Altbach, M.I., Squire, S.W., Kudi-Thipudi, V., Castellano, L. and Sorrell, V.L. (2007) Cardiac MRI Is Complementary to Echocardiography in the Assessment of Cardiac Masses. Echocardiography, 24, 286-300. https://doi.org/10.1111/j.1540-8175.2007.00392.x