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2型DKD患者血清焦亡相关蛋白与肾损伤的分析
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Abstract:
糖尿病肾病(DKD)是糖尿病最常见的并发症之一，也是导致终末期肾病的主要原因。全球30%~40%糖尿病患者因病情迁延而进展至DKD，伴有终末期肾病的患者五年生存率 < 20%。因此，延缓DKD进展对于改善患者生存质量具重大意义。目前研究发现，2型DKD发病进展中的无菌性炎症机制与病情进展密切相关。
Diabetic nephropathy (DKD) is one of the most common complications of diabetes and the main cause of end-stage renal disease. Globally, 30%~40% of diabetic patients progress to DKD due to disease delay, and the five-year survival rate of patients with end-stage re-nal disease is less than 20%. Therefore, delaying DKD progression is of great significance for im-proving patients’ quality of life. Current studies have found that the aseptic inflammatory mecha-nism in the progression of type 2 DKD is closely related to the progression of the disease.
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