一种高纯度噻唑磷的合成与分析
A Kind of Synthesis and Analysis of Thiazophos with High Purity

[目的]提出一种合成噻唑磷的新型实验方案。[方法]以噻唑烷酮(1,3-噻唑烷-2-酮)和磷酰氯(S-仲丁基-O-乙基硫代磷酰氯)为原料，在甲苯溶液中，通过氢化钠和催化剂的加持下，合成并分离提纯出噻唑磷((RS)-S-仲丁基-O-乙基-2-氧代-1，3-噻唑烷-3-基硫代瞵酸酯)这一新型杀虫剂，通过红外光谱、紫外光谱、高效液相色谱(HPLC)以及气相色谱(GC)等表征手段，对产物噻唑磷进行详细的分析。[结果]催化剂有别于传统催化剂，带来了新方案的同时也提升了产率，合成的噻唑磷浓度可大于等于97%，同时产率大于67%。[结论]该方法操作简单，环保安全，且新型催化剂的加入保证了产率和产物浓度，有很大的实用价值。
[Aims] A novel experimental scheme for the synthesis of thiazole phosphorus was proposed. [Method] Thiazolidinone (1,3-thiazolidinone-2-one) and phosphoryl chloride (s-sec-butyl-o-ethyl thiophosphoryl chloride) were used as raw materials. In toluene solution, supported by sodium hydride and catalyst, thiazolidinophos ((RS)-s-sec-butyl-o-ethyl-2-oxo-1, 3-thiazolidinyl-3-thioxanthate) was synthesized and purified as a new insecticide. The product thiazophos was analyzed by in-frared spectrum, ultraviolet spectrum, high performance liquid chromatography (HPLC) and gas chromatography (GC). [Results] The catalyst was different from the traditional catalyst, which not only brought new scheme but also improved the yield. The synthesized thiazole phosphorus concentration could be greater than or equal to ninety-seven percent, and the yield was greater than 67%. [Conclusion] The method was simple in operation, environmentally friendly and safe. In addition, the addition of new catalyst ensured the yield and product concentration, so it had great practical value.