Background: Electronic
cigarettes were originally designed to reduce adult dependency on normal
cigarettes and as a tobacco cessation tool to substitute traditional
cigarettes. But it has become the most popular among teenagers. Rationale: To
investigate the immediate adverse respiratory effect of short-term electronic cigarette vapor inhalation. Method: Twenty-five subjects were randomly selected and used in this study. The
respiratory resistance values were evaluated and used for comparison. The
subjects were asked to breathe into the Airflow Perturbation Device (APD) for
evaluation of their respiratory resistance before vaping (in triplicate). The
same subjects, a minute later, were then asked to use one poke (3 seconds) of
the e-Cigarette device to inhale e-Cigarette vapor with nicotine from a pod
with 59 mg/ml nicotine. Immediately following the e-Cigarette use, their
respiratory resistance was measured again (in triplicate). Results: Comparing the respiratory resistance values before and immediately after
exposure to e-Cigarette vapor showed that their respiratory resistance
increased almost immediately. Conclusion: Although there are long-term
studies showing that the e-Cigarette is as harmful as regular cigarettes, this
study showed a nearly immediate effect of using the e-Cigarette that
significantly increased the respiratory resistance of the user. Very short
exposure time to e-Cigarette vapor (3 seconds only), caused an immediate
adverse physiologic effect in respiratory resistance.
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