Introduction: The aim
was to identify the etiologies of generalised pruritus sine materia and
to determine the associated factors in Parakou. Methods: This was a
retrospective observational study conducted from January 2011 to June 2022. The
patients included were of all ages and both sexes in whom the sine materia nature
of the pruritus was noted after clinical examination. These patients had an
etiological assessment available or not, complete or partial. For each patient,
socio-demographic, socio-cultural, socio-economic and clinical data were
collected using a pre-established survey form. They were then processed and
analysed using Epi Data 3.1 and SPSS version 21 software respectively. Results: Theincidence of generalised pruritus sine materia was 0.89%
(73 cases/8214 consultants). The predominant etiologies were aquagenic pruritus
(16.4%) and intestinal parasitosis (12.3%). After a bi-variate analysis, two
risk factors were identified: frequency of towel change greater than 1 month
(OR = 3.02; CI95% = 0.98-9.31; P = 0.0486)
and use of cold water for bath (OR = 3.28; CI95% = 1.09-9.81; P = 0.0274). Conclusion: The etiologies and associated factors of generalised
pruritus sine materia found in Parakou are varied but are linked to
lifestyle. There is an urgent need to raise public awareness of the need to
improve lifestyle in order to reduce the frequency of pruritus sine materia.
References
[1]
Gallen, C. and Raison-Peyron, N. (2011) Orientation diagnostique et conduite à tenir devant un prurit. Revue Française d’Allergologie, 51, S29-S32.https://doi.org/10.1016/S1877-0320(11)70030-6
[2]
Lorette, G., Maruani, A. (2009) Prurit. In: Saurat, J.H., Lachapelle, J.M., Lipsker, D. and Thomas, L., Eds., Dermatologie et maladies sexuellement transmissibles, 5th Edition, Elsevier Masson, Paris, 1005-1012.
[3]
Pitché, P., Bahoundé, A., Agbo, K. and Tchangaï-Walla, K. (1996) Les étiologies des prurits isolés en consultation de dermatologie à Lomé. Cahiers Santé, 6, 17-19.
[4]
Dalgrad, F., Holm, J., Svensson, A., Kumar, B. and Sundby, J. (2007) Self Reported Skin Morbidity and Ethnicity: A Population-Based Study in a Western Community. BMC Dermatology, 7, Article No. 4. https://doi.org/10.1186/1471-5945-7-4
[5]
Dalgrad, F., Svensson, A., Holm, J. and Sundby, J. (2004) Self Reported Skin Morbidity in Oslo. Associations with Sociodemographic Factors among Adults in a Cross-Sectional Study. British Journal of Dermatology, 151, 452-457.https://doi.org/10.1111/j.1365-2133.2004.06058.x
[6]
Ständer, S., Zeidler, C., Augustin, M., Bayer, G., Kremer, A.E. and Legat, F.J. (2017) Guidelines for the Diagnosis and Treatment of Chronic Pruritus-Update-Short Version. Journal der Deutschen Dermatologischen Gesellschaft, 15, 860-872. https://doi.org/10.1111/ddg.13304
[7]
Misery, L. (2014) Le prurit: Des avancées physiopathologiques considérables. Medical Sciences, 30, 1123-1128. https://doi.org/10.1051/medsci/20143012015
[8]
Robert, M., Misery, L. and Brenaut, E. (2020) Etiologie des prurits sine materia: Une étude rétrospective de 197 patients. Annales de Dermatologie et de Vénérologie, 147, A306. https://doi.org/10.1016/j.annder.2020.09.458
[9]
Dégboé, B., Kouassi-Ibrahim, A., Maffo Kamgaing, N., Akpadjan, F., Adégbidi, H. and Atadokpèdé, F. (2021) Prurit généralisé sine materia en Dermatologie à Cotonou (Bénin). Revue internationale des Sciences Médicales d’Abidjan (RISM), 23, 30-36.
[10]
Alizadeh, N., Mirpour, S.H., Golmohamadi, R., Darjani, A., Eftekhari, H., Rafiei, R., et al. (2018) Chronic Generalised Pruritus without Primary Skin Lesions: A Longitudinal Prospective Observational Study. International Journal of Dermatology, 58, 273-278. https://doi.org/10.1111/ijd.14125
[11]
Olumide, Y.M. and Oresanya, F. (1987) Generalized Pruritus as a Presenting Symptom in Nigeria. International Journal of Dermatology, 26, 171-173.https://doi.org/10.1111/j.1365-4362.1987.tb00885.x
[12]
Doe, P.T., Asiedu, A., Acheampong, J.W. and Rowland Payne, C.M.E. (2001) Skin diseases in Ghana and the UK. International Journal of Dermatology, 40, 323-326.https://doi.org/10.1046/j.1365-4362.2001.01229.x
[13]
Cassano, N., Tessari, G., Vena, G.A. and Girolomoni, G. (2010) Chronic Pruritus in the Absence of Specific Skin Disease: An Update on Pathophysiology, Diagnosis, and Therapy. American Journal of Clinical Dermatology, 11, 399-411.https://doi.org/10.2165/11317620-000000000-00000
[14]
Goffin, V., Dawlati, A., Cornil, F. and Pierard, G.E. (1993) Prurit. In: Pierard, G.E., Caumes, E., Franchimont, C. and Estrada, J.A., Eds., Dermatologie Tropicale, Aupelf, Bruxelles, 575-578.
[15]
Misery, L. (2006) Prurit. In: EMC-Dermatologie, Article 98-140-A-10.
[16]
Mazereeuw, J. and Bonafé, J.-L. (2002) Xerosis. Annales de Dermatologie et de Vénéréologie, 129, 137-142.
[17]
Afifi, Y., Aubin, F., Puzenat, E., Degouy, A., Aubrion, D., Hassam, B. and Humbert, P. (2004) Enquête étiologique d’un prurit sine materia. La Revue de Médecine Interne, 25, 490-493. https://doi.org/10.1016/j.revmed.2003.12.015
[18]
Cao, T., Tey, H.L. and Yosipovitch, G. (2018) Chronic Pruritus in the Geriatric Population. Dermatologic Clinics, 36, 199-211.https://doi.org/10.1016/j.det.2018.02.004
