Glutathione peroxidase (GPx) is an antioxidant that
plays an important role in the maintenance of male fertility. The aim of this study was to compare the profile of
enzymatic activity of glutathione peroxidase in the seminal plasma of
normozoosperm and those of pathological sperm. Thus, the activity of
glutathione peroxidase was determined in the seminal plasma of 20 normozoosperms, 9 azoosperms and 31 oligoasthenoteratozoosperms. It was 37.58 ± 3.14 U/L in normozoosperms, 39.39 ±
2.27 U/L in oligoasthenoteratozoosperms, and 29.77 ± 2.62 U/L in azoosperms.
The mean GPx enzyme activity of normozoosperms did not differ significantly
from that of oligoasthenoteratozoosperms and azoosperms. In contrast,
comparison of enzyme activity between abnormal sperms gave a significant difference. This study showed that glutathione peroxidase
enzymatic activity is not related to sperm quality.
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