Background: Non-invasive facial treatments have the ability to rejuvenate the facial profile
when specific pharmacologic agents and modalities are prescribed and used in
combination taking into consideration each patient’s unique skin type and
condition. RATIONALE Epinova is a non-invasive skin treatment that combines the
correct concentrations and combinations of topicals and modalities to elicit
facial rejuvenation with no down-time or side effects.Purpose: This paper focuses on facial rejuvenation improvements combining the
RATIONALE Essential Six skincare system (RATIONALE, Victoria, Australia) to protect and repair the skin with the
RATIONALE Epinova facial treatment every 4-6 weeks—which uses non-invasive technologies and professional strength
active ingredients to deliver visible changes to skin tone and texture. Methods: Subjects underwent a RATIONALE consultation, including taking a skin
history and skin imaging, followed by a data analysis
and diagnosis of skin condition and prescription of a customized RATIONALE
treatement (Epinova), including appropriate pharmacologic agents and treatment
with personalized photo/sono therapeutic devices. Results: Subjects
reported increased skin hydration, tactile improvements, skin firmness and
visible radiance following the RATIONALE Epinova treatment. Further
investigations will be initiated to explore the potential for longer term
improvements, including connenctive tissue deposition, reduction of erythema
etc. Treatments should be performed every 4-6 weeks
for patients under 40 and every 3-4 weeks
for patients over 40, to support cell differentiation,
migration and desquamation to achieve non-invasive facial rejuvenation. Conclusion: This study demonstrated that the synergy of pharmacologic, LED light
therapy and ultrasonic technologies when prescribed and administered by a trained skin therapist, can lead to
a visible improvement in the signs of facial ageing and photodamage,
restoring the appearance
References
[1]
Goldsberry, A., Hanke, C.W. and Hanke, K.E. (2014) VISIA System: A Possible Tool in the Cosmetic Practice. Journal of Drugs in Dermatology, 13, 1312-1314.
[2]
Tanaka, Y. (2019) Long-Term Objective Assessments of Skin Rejuvenation Using Solar Protection and Solar Repair Shown through Digital Facial Surface Analysis and Three-Dimensional Volumetric Assessment. Clinical, Cosmetic and Investigational Dermatology, 12, 553-561. https://doi.org/10.2147/CCID.S218176
[3]
Kuo, S.H., Shen, C.J., Shen, C.F. and Cheng, C.M. (2020) Role of pH Value in Clinically Relevant Diagnosis. Diagnostics (Basel), 10, 107. https://doi.org/10.3390/diagnostics10020107
[4]
Samuels, L.E. (2010) Understanding the Science behind pH and Its Role in Younger, Healthier-Looking Skin. Cosmetic Dermatology, 23, 562-567.
[5]
Bagatin, E. and Guadanhim, L.R. (2016) Hydroxy Acids. In: Daily Routine in Cosmetic Dermatology, 1-15. https://doi.org/10.1007/978-3-319-20250-1_16-1
[6]
Cheong-Qi Seah, B. and Teo, B.M. (2018) Recent Advances in Ultrasound-Based Transdermal Drug Delivery. International Journal of Nanomedicine, 13, 7749-7763. https://doi.org/10.2147/IJN.S174759
[7]
Khan, U. and Khalid, N.A. (2021) Systematic Review of the Clinical Efficacy of Micro-Focused Ultrasound Treatment for Skin Rejuvenation and Tightening. Cureus, 13, e20163. https://doi.org/10.7759/cureus.20163
[8]
Vranić, E. (2004). Sonophoresis-Mechanisms and Application. Biomol Biomed, 4, 25-32. https://doi.org/10.17305/bjbms.2004.3410
[9]
Bravo, B., Correia, P., Goncalves, J.E., Sant’Anna, B. and Kerob, D. (2022) Benefits of Topical Hyaluronic Acid for Skin Quality and Signs of Skin Aging: From Literature Review to Clinical Evidence. Dermatologic Therapy, 35, e15903. https://doi.org/10.1111/dth.15903
[10]
Calderhead, G. and Tanaka, Y. (2017) Photobiological Basics and Clinical Indications of Phototherapy for Skin Rejuvenation. In: Photomedicine: Advances in Clinical Practice, InTech, 215-252. https://doi.org/10.5772/intechopen.68723 https://www.intechopen.com/books/photomedicine-advances-in-clinical-practice/photobiological-basics-and-clinical-indications-of-phototherapy-for-skin-rejuvenation
[11]
Tanaka, Y. and Gale, L. (2013) Beneficial Applications and Deleterious Effects of Near-Infrared from Biological and Medical Perspectives. Optics and Photonics Journal, 3, 31-39. https://doi.org/10.4236/opj.2013.34A006
[12]
Diogo, M.L.G., Campos, T.M., Fonseca, E.S.R., Pavani, C., Horliana, A.C.R.T., Fernandes, K.P.S., Bussadori, S.K., Fantin, F.G.M.M., Leite, D.P.V., Yamamoto, Â.T.A., Navarro, R.S. and Motta, L.J. (2021) Effect of Blue Light on Acne Vulgaris: A Systematic Review. Sensors (Basel), 21, 6943. https://doi.org/10.3390/s21206943
[13]
Tanaka, Y. (2020) Three-Dimensional Quantification of Skin Surface Displacement Following Skin Rejuvenation Using Solar Protection and Solar Repair. The Journal of Clinical and Aesthetic Dermatology, 13, 47-50.
[14]
Tanaka, Y. (2023) Photoprotective Ability of Sunscreens against Ultraviolet, Visible Light and Near-Infrared Radiation. Optics and Photonics Journal, 13, 140-146. https://doi.org/10.4236/opj.2023.136012
[15]
Tanaka, Y., Parker, R. and Aganahi, A. (2023) Photoprotective Ability of Colored Iron Oxides in Tinted Sunscreens against Ultraviolet, Visible Light and Near-Infrared Radiation. Optics and Photonics Journal, 13, 199-208. https://doi.org/10.4236/opj.2023.138018
[16]
Tanaka, Y., Parker, R., Aganahi, A. and Pedroso, A. (2023) Novel Low Viscosity Zinc Oxide, Iron Oxides and Erioglaucine Sunscreen Potential to Protect from Ultraviolet, Visible Light and Near-Infrared Radiation. Optics and Photonics Journal, 13, 217-226. https://doi.org/10.4236/opj.2023.139020
[17]
Tanaka, Y., Parker, R. and Aganahi, A. (2023) Up-Regulated Expression of ICAM1, MT1A, PTGS2, LCE3D, PPARD, and GM-CSF2 Following Solar Skincare Protection and Repair Strategies in a 3-Dimensional Reconstructed Human Skin Model. Clinical, Cosmetic and Investigational Dermatology, 16, 2829-2839. https://doi.org/10.2147/CCID.S428170