Epidemiological Profile of Cyanotic Congenital Heart Disease in the “B” Surgery Department of Point G University Hospital, before the Advent of Extracorporeal Circulation
Aim: Evaluate the epidemiological profile of cyanotic congenital heart
disease in Mali before the advent of extracorporeal circulation in the “B” Surgery Department at the Pont G University
Hospital. Patients and Methods: This was a retrospective and descriptive
study that took place from January 1, 2011 to December 31, 2017. The records of
patients with cyanotic congenital heart disease in the “B” surgery department of Point G University Hospital were collected. Patients
operated on for cyanotic congenital heart disease were included in this study.
Non-operated patients were not included. Results: The records of 17
patients operated on for cyanotic congenital heart disease were retained. The
average age of patients at the time of surgery was 5.18 years with extremes of
2 and 18 years. Boys were in the majority with 59%, i.e. a sex ratio of 1.42. Patients resided in Bamako in 82% of
cases. Inbreeding was found in 35.3%. Eighty-eight percent of children were
born at term and 94% had up-to-date vaccination status. The average duration of
patient follow-up between diagnosis and surgical management was 5 years with
extremes of 2 years and 12 years. Tetralogy of Fallot regular form was the most
represented heart disease. Conclusion: Cyanogenic congenital heart
disease remains the most frequent congenital pathologies in our country. They
most often affect male children. Consanguinity is the most common etiological
factor found. Tetralogy of Fallot regular form remains the most common.
References
[1]
Robert-Gnansia, E., Francannet, C., Bozio, A. and Bouvagnet, P. (2004) Epidemiology, Etiology and Genetics of Congenital Heart Disease. EMC Cardiology-Angiology, 1, 140-160. https://doi.org/10.1016/j.emcaa.2004.02.002
[2]
Cloarec, S., Magontier, N., Vaillant, M.C., Paillet, C. and Chantepie, A. (1999) Prevalence and Distribution of Congenital Heart Disease in Indre-et-Loire. Evaluation of Antenatal Diagnosis (1991–1994). Archives of Pediatrics, 6, 1059-1065. https://doi.org/10.1016/S0929-693X(00)86979-1
[3]
Arlettaz, R. (2005) Recommendations Concerning Neonatal Screening for Congenital Heart Disease. Pediatrica, 16, 38-41.
[4]
Baudet, E. (2004) Surgery for Congenital Heart Disease. Archives of Pediatrics, 11, 642-644. https://doi.org/10.1016/j.arcped.2004.03.084
[5]
Eloi, M., Tivane, A., Voicu, S., Alda, V., Jani, D., Freereira, B., et al. (2006) Incidence of Congenital Heart Disease in Schoolchildren in Sub-Saharan Africa, Mozambique. International Journal of Cardiology, 113, 440-441. https://doi.org/10.1016/j.ijcard.2006.06.049
Gillum, R.F. (1994) Epidemiology of Congenital Heart Disease in the United States. American Heart Journal, 127, 919-927. https://doi.org/10.1016/0002-8703(94)90562-2
[8]
Ndongo-Amougou, S., Jingi, A.M., Otseng Abe, A., Owona, A., Hamadou, B., Chelo, D. and Kingue, S. (2022) Epidemiological, Clinical and Therapeutic Aspects of Congenital Heart Disease in Two Hospitals in Yaoundé: A Cross-Sectional Study. Archives of Cardiovascular Diseases Supplements, 14, 115. https://doi.org/10.1016/j.acvdsp.2021.09.261
[9]
Diby Kouakou Florent, Azagoh-Kouadio R, Yao Kouassi C, Yeboua Kossonou R, Aka-Tanoh Aude Hélène et al. (2019) Epidemiological, Clinical and Evolutionary Profile of Congenital Heart Disease in Côte d’Ivoire: Retrospective Multicenter Study. Revue Internationale des Sciences Médicales, 21, 293-300.
[10]
Siu, S.C. and Silversides, C.K. (2010) Bicuspid Aortic Valve Disease. Journal of the American College of Cardiology, 55, 2789-2800. https://doi.org/10.1016/j.jacc.2009.12.068
[11]
Moons, P., Sluysmans, T., De Wolf, D., Massin, M., Suys, B., Benatar, A., et al. (2009) Congenital Heart Disease in 111, 225 Births in Belgium: Birth Prevalence, Treatment and Survival in the 21st Century. Acta Paediatrica, 98, 472-477. https://doi.org/10.1111/j.1651-2227.2008.01152.x
[12]
Aubry, P. and Demian, H. (2016) Gender Differences in Congenital Heart Disease. Annals of Cardiology and Angiology, 65, 440-445. https://doi.org/10.1016/j.ancard.2016.10.006
[13]
Somerville, J. (1998) The Woman with Congenital Heart Disease. European Heart Journal, 19, 1766-1775. https://doi.org/10.1053/euhj.1998.1204
[14]
Sampayo, F. and Pinto, F.F. (1994) Sex Distribution of Congenital Heart Disease. Acta Médica Portuguesa, 7, 413-418.
[15]
Michalski, A.M., Richardson, S.D., Browne, M.L., Carmichael, S.L., Canfield, M.A., VanZutphen, A.R., et al. (2015) Sex Ratios among Infants with Birth Defects, National Birth Defects Prevention Study, 1997-2009. American Journal of Medical Genetics Part A, 167, 1071-1081. https://doi.org/10.1002/ajmg.a.36865
[16]
Warnes, C.A. (2008) Sex Differences in Congenital Heart Disease. Should a Woman Be More Like a Man? Circulation, 118, 3-5. https://doi.org/10.1161/CIRCULATIONAHA.108.785899
[17]
Talwar, S. Choudhary, S.K. and Mathur, A. (2008) Changing Outcomes of Pulmonary Artery Banding with the Percutaneously Adjustable Pulmonary Artery Band. The Annals of Thoracic Surgery, 85, 593-598. https://doi.org/10.1016/j.athoracsur.2007.07.057
[18]
Yoshimura, N., Yamaguchi, M., Oka, S., Yoshida, M. and Murakami, H. (2005) Pulmonary Artery Banding Still Has an Important Role in the Treatment of Congenital Heart Disease. The Annals of Thoracic Surgery, 79, 1463. https://doi.org/10.1016/j.athoracsur.2003.12.113
[19]
Baslaim, G. (2009) Modification of Trusler’s Formula for the Pulmonary Artery Banding. Heart, Lung and Circulation, 18, 353-357. https://doi.org/10.1016/j.hlc.2009.02.003
[20]
Nazari, P. (2016) Prevalence of Congenital Heart Disease: A Single Center Experience in Southwestern of Iran. Global Journal of Health Science, 8, 288-294. https://doi.org/10.5539/gjhs.v8n10p288
[21]
Majeed-Saidanam, M.A., et al. (2015) Effect of Consanguinity on Birth Defects in Saudi Women: Results from a Nested Case-Control Study. Clinical and Molecular Tetralogy, 103, 100-104. https://doi.org/10.1002/bdra.23331